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Applied Therapeutics
APLT

Overview Fund Activity

90 hedge funds and large institutions have $51.8M invested in Applied Therapeutics in 2025 Q1 according to their latest regulatory filings, with 13 funds opening new positions, 27 increasing their positions, 32 reducing their positions, and 40 closing their positions.

Holders
90
Holders Change
-28
Holders Change %
-23.73%
% of All Funds
1.22%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
13
Increased
27
Reduced
32
Closed
40
Calls
$226K
Puts
$97K
Net Calls
+$129K
Net Calls Change
-$323K

Top Buyers

1
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$5.08M
2
KCM
2
Knoll Capital Management
Florida
$3.81M
3
SAM
3
Simplify Asset Management
Nevada
$2.19M
4
PBM
4
Propel Bio Management
California
$5.52M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$470K

Top Sellers

1
Morgan Stanley
1
Morgan Stanley
New York
$1.4M
2
VA
2
VR Adviser
New York
$2.72M
3
SSA
3
Schonfeld Strategic Advisors
New York
$2.28M
4
SL
4
Siren LLC
Connecticut
$0
5
Citadel Advisors
5
Citadel Advisors
Florida
$0
Name Market Value Shares Shares
Change 		Shares
Change %
AC
101
Aristides Capital
Kentucky
– – -156,507 Closed
Swiss National Bank
102
Swiss National Bank
Switzerland
– – -146,900 Closed
UBS AM
103
UBS AM
Illinois
– – -119,035 Closed
SRL
104
Scientech Research LLC
New Jersey
– – -76,511 Closed
DFCM
105
Dark Forest Capital Management
Puerto Rico
– – -53,718 Closed
State of Wisconsin Investment Board
106
State of Wisconsin Investment Board
Wisconsin
– – -51,526 Closed
Jane Street
107
Jane Street
New York
– – -51,049 Closed
GCP
108
GSA Capital Partners
United Kingdom
– – -50,994 Closed
LCM
109
Laurion Capital Management
New York
– – -50,000 Closed
Janus Henderson Group
110
Janus Henderson Group
United Kingdom
– – -35,791 Closed
GSC
111
Ground Swell Capital
South Carolina
– – -31,636 Closed
WP
112
Woodline Partners
California
– – -26,786 Closed
Zurich Cantonal Bank
113
Zurich Cantonal Bank
Switzerland
– – -25,778 Closed
Teacher Retirement System of Texas
114
Teacher Retirement System of Texas
Texas
– – -23,202 Closed
Russell Investments Group
115
Russell Investments Group
United Kingdom
– – -21,648 Closed
ASRS
116
Arizona State Retirement System
Arizona
– – -21,619 Closed
VF
117
Virtu Financial
New York
– – -21,414 Closed
D.E. Shaw & Co
118
D.E. Shaw & Co
New York
– – -17,799 Closed
Pictet Asset Management
119
Pictet Asset Management
Switzerland
– – -16,963 Closed
Wolverine Trading
120
Wolverine Trading
Illinois
– – -16,573 Closed
KK
121
KLP Kapitalforvaltning
Norway
– – -15,100 Closed
Mariner
122
Mariner
Kansas
– – -12,328 Closed
Canada Life
123
Canada Life
Manitoba, Canada
– – -9,427 Closed
LP
124
LMR Partners
United Kingdom
– – -4,500 Closed
ACM
125
Aster Capital Management
United Arab Emirates
– – -2,949 Closed
2 3 4
5
6