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Applied Therapeutics
APLT

Overview Fund Activity

72 hedge funds and large institutions have $27.2M invested in Applied Therapeutics in 2025 Q2 according to their latest regulatory filings, with 14 funds opening new positions, 15 increasing their positions, 30 reducing their positions, and 29 closing their positions.

Holders
72
Holders Change
-18
Holders Change %
-20%
% of All Funds
0.97%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
14
Increased
15
Reduced
30
Closed
29
Calls
$131K
Puts
$68K
Net Calls
+$63K
Net Calls Change
-$66K

Top Buyers

1
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$5.79M
2
Pathstone Holdings
2
Pathstone Holdings
New Jersey
$822K
3
Millennium Management
3
Millennium Management
New York
$605K
4
Citadel Advisors
4
Citadel Advisors
Florida
$147K
5
Goldman Sachs
5
Goldman Sachs
New York
$227K

Top Sellers

1
VA
1
VR Adviser
New York
$0
2
Alyeska Investment Group
2
Alyeska Investment Group
Illinois
$0
3
SSA
3
Schonfeld Strategic Advisors
New York
$61.2K
4
BlackRock
4
BlackRock
New York
$1.62M
5
Deutsche Bank
5
Deutsche Bank
Germany
$193K
Name Market Value Shares Shares
Change 		Shares
Change %
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$5.79M 18,683,990 +8,303,400 +80%
VPC
2
Vestal Point Capital
New York
$3.58M 11,500,000 – –
PBM
3
Propel Bio Management
California
$3.51M 11,285,420 – –
KCM
4
Knoll Capital Management
Florida
$2.43M 7,799,687 – –
BlackRock
5
BlackRock
New York
$1.62M 5,219,686 -4,331,616 -45%
Vanguard Group
6
Vanguard Group
Pennsylvania
$1.47M 4,734,013 -1,155,180 -20%
SAM
7
Simplify Asset Management
Nevada
$1.4M 4,487,505 – –
Pathstone Holdings
8
Pathstone Holdings
New Jersey
$822K 2,643,540 +2,643,540 New
TCM
9
Tang Capital Management
California
$755K 2,428,169 – –
RSCM
10
Rock Springs Capital Management
Maryland
$646K 2,075,991 +1,100 +0.1%
Franklin Resources
11
Franklin Resources
California
$623K 2,003,338 – –
Millennium Management
12
Millennium Management
New York
$605K 1,944,904 +1,835,806 +1,683%
Qube Research & Technologies (QRT)
13
Qube Research & Technologies (QRT)
United Kingdom
$567K 1,822,569 -116,435 -6%
Marshall Wace
14
Marshall Wace
United Kingdom
$479K 1,544,191 +236,810 +18%
Adage Capital Partners
15
Adage Capital Partners
Massachusetts
$377K 1,211,629 -750,000 -38%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$301K 968,541 -1,182,851 -55%
UBS Group
17
UBS Group
Switzerland
$258K 830,645 +325,538 +64%
Goldman Sachs
18
Goldman Sachs
New York
$227K 730,718 +414,488 +131%
Deutsche Bank
19
Deutsche Bank
Germany
$193K 622,227 -3,844,358 -86%
Two Sigma Investments
20
Two Sigma Investments
New York
$185K 594,534 -366,053 -38%
Citadel Advisors
21
Citadel Advisors
Florida
$147K 474,094 +474,094 New
Charles Schwab
22
Charles Schwab
California
$126K 403,514 -229,015 -36%
State Street
23
State Street
Massachusetts
$110K 352,377 -1,598,532 -82%
Morgan Stanley
24
Morgan Stanley
New York
$107K 342,636 -2,529,588 -88%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$94.5K 303,900 -354,500 -54%
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