Apogee Therapeutics
APGE
168 hedge funds and large institutions have $2.3B invested in Apogee Therapeutics in 2025 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 50 increasing their positions, 59 reducing their positions, and 21 closing their positions.
57% more first-time investments, than exits
New positions opened: 33 | Existing positions closed: 21
50% more call options, than puts
Call options by funds: $14.3M | Put options by funds: $9.54M
7% more funds holding
Funds holding: 157 → 168 (+11)
5.09% more ownership
Funds ownership: 128.52% → 133.61% (+5.1%)
0% more funds holding in top 10
Funds holding in top 10: 4 → 4 (0)
12% less capital invested
Capital invested by funds: $2.62B → $2.3B (-$320M)
15% less repeat investments, than reductions
Existing positions increased: 50 | Existing positions reduced: 59
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Wellington Management Group
Boston,
Massachusetts
|
+$37.4M |
| 2 |
JP Morgan Chase
New York
|
+$35.8M |
| 3 |
Mercer Global Advisors
Denver,
Colorado
|
+$35.6M |
| 4 |
Janus Henderson Group
London,
United Kingdom
|
+$25.5M |
| 5 |
PCH
Polar Capital Holdings
London,
United Kingdom
|
+$21.3M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
JFG
Jefferies Financial Group
New York
|
-$18M |
| 2 |
LGM
Logos Global Management
San Francisco,
California
|
-$13.6M |
| 3 |
PBA
Paradigm Biocapital Advisors
New York
|
-$12.5M |
| 4 |
DCM
Driehaus Capital Management
Chicago,
Illinois
|
-$10.3M |
| 5 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$8.92M |
APGE Hedge Fund Activity: Q1 2025 in Review
168 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Apogee Therapeutics (APGE) for Q1 2025, worth a combined $2.3B — down 12% from $2.62B a quarter earlier.
Buyers outnumbered sellers: 33 funds opened new APGE positions and 21 closed out — a net gain of 12 holders — while 50 added to existing stakes and 59 trimmed.
The largest buyer was Wellington Management Group, adding an estimated $37.4M. The largest seller was Jefferies Financial Group, cutting an estimated $18M.
- 168 institutional investors held Apogee Therapeutics (APGE) as of Q1 2025, up from 157 in Q4 2024.
- Funds reported $2.3B of Apogee Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
- 33 funds opened new Apogee Therapeutics positions in Q1 2025 and 21 closed out, a net change of +12 holders.
- The largest Apogee Therapeutics buyer in Q1 2025 was Wellington Management Group, an estimated $37.4M added.
- The largest Apogee Therapeutics seller in Q1 2025 was Jefferies Financial Group, an estimated $18M sold.
Based on aggregated 13F filings for Q1 2025.