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Apogee Therapeutics
APGE

168 hedge funds and large institutions have $2.3B invested in Apogee Therapeutics in 2025 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 50 increasing their positions, 59 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

57% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 21

50% more call options, than puts

Call options by funds: $14.3M | Put options by funds: $9.54M

7% more funds holding

Funds holding: 157 → 168 (+11)

5.09% more ownership

Funds ownership: 128.52% → 133.61% (+5.1%)

0% more funds holding in top 10

Funds holding in top 10: 4 → 4 (0)

12% less capital invested

Capital invested by funds: $2.62B → $2.3B (-$320M)

15% less repeat investments, than reductions

Existing positions increased: 50 | Existing positions reduced: 59

Holders
168
Holders Change
+11
Holders Change %
+7.01%
% of All Funds
2.25%
Holding in Top 10
4
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
33
Increased
50
Reduced
59
Closed
21
Calls
$14.3M
Puts
$9.54M
Net Calls
+$4.8M
Net Calls Change
+$6.41M

Top Buyers

Rank Fund Capital Flow
1
Wellington Management Group
Wellington Management Group
Massachusetts
+$37.4M
2
JP Morgan Chase
JP Morgan Chase
New York
+$35.8M
3
Mercer Global Advisors
Mercer Global Advisors
Colorado
+$35.6M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$25.5M
5
PCH
Polar Capital Holdings
United Kingdom
+$21.3M

Top Sellers

Rank Fund Capital Flow
1
JFG
Jefferies Financial Group
New York
-$18M
2
LGM
Logos Global Management
California
-$13.6M
3
PBA
Paradigm Biocapital Advisors
New York
-$12.5M
4
DCM
Driehaus Capital Management
Illinois
-$10.3M
5
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$8.92M
Name Holding Trade Value Shares
Change 		Change in
Stake
RAM
176
Readystate Asset Management
Illinois
– -$1.06M -23,400 Closed
JF
177
Jump Financial
Illinois
– -$945K -20,867 Closed
Verition Fund Management
178
Verition Fund Management
Connecticut
– -$882K -19,477 Closed
SG Americas Securities
179
SG Americas Securities
New York
– -$448K -9,890 Closed
Allianz Asset Management
180
Allianz Asset Management
Germany
– -$313K -6,900 Closed
SO
181
STRS Ohio
Ohio
– -$249K -5,500 Closed
AQR Capital Management
182
AQR Capital Management
Connecticut
– -$243K -5,365 Closed
AIM
183
Aigen Investment Management
New York
– -$216K -4,767 Closed
OF
184
Optimize Financial
California
– -$203K -4,473 Closed
VEA
185
Virtus ETF Advisers
New York
– -$72.7K -1,604 Closed
SAM
186
Smartleaf Asset Management
Massachusetts
– -$3.66K -82 Closed
Simplex Trading
187
Simplex Trading
Illinois
– -$2.82K -73 Closed
CIAM
188
Caitong International Asset Management
Hong Kong
– -$1.86K -41 Closed
PA
189
Parallel Advisors
California
– -$272 -6 Closed
4 5 6 7
8

APGE Hedge Fund Activity: Q1 2025 in Review

168 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Apogee Therapeutics (APGE) for Q1 2025, worth a combined $2.3B — down 12% from $2.62B a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new APGE positions and 21 closed out — a net gain of 12 holders — while 50 added to existing stakes and 59 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $37.4M. The largest seller was Jefferies Financial Group, cutting an estimated $18M.

  • 168 institutional investors held Apogee Therapeutics (APGE) as of Q1 2025, up from 157 in Q4 2024.
  • Funds reported $2.3B of Apogee Therapeutics stock for Q1 2025, down 12% quarter-over-quarter.
  • 33 funds opened new Apogee Therapeutics positions in Q1 2025 and 21 closed out, a net change of +12 holders.
  • The largest Apogee Therapeutics buyer in Q1 2025 was Wellington Management Group, an estimated $37.4M added.
  • The largest Apogee Therapeutics seller in Q1 2025 was Jefferies Financial Group, an estimated $18M sold.

Based on aggregated 13F filings for Q1 2025.