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ANRO

Name Holding Trade Value Shares
Change 		Change in
Stake
AWG
1
Alpha Wave Global
New York
$56.9M +$58M +3,707,757 New
Fidelity Investments
2
Fidelity Investments
Massachusetts
$36.1M +$36.8M +2,349,916 New
RCM
3
RA Capital Management
Massachusetts
$21.3M +$21.7M +1,385,491 New
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$17.3M +$17.6M +1,125,000 New
7IH
5
72 Investment Holdings
Connecticut
$10.3M +$10.5M +667,778 New
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$9.79M +$9.98M +637,604 New
Franklin Resources
7
Franklin Resources
California
$9.59M +$9.78M +625,012 New
ECM
8
ExodusPoint Capital Management
New York
$9.31M +$9.5M +606,730 New
DTC
9
Deep Track Capital
Connecticut
$9.21M +$9.39M +600,000 New
Vanguard Group
10
Vanguard Group
Pennsylvania
$8.23M +$8.39M +536,332 New
Jennison Associates
11
Jennison Associates
New York
$7.04M +$7.18M +458,599 New
PFMOSF
12
Philadelphia Financial Management of San Francisco
California
$6.68M +$6.82M +435,489 New
AG
13
Artal Group
Luxembourg
$5.37M +$5.48M +350,000 New
BOTOTLSJU
14
Board of Trustees of The Leland Stanford Junior University
California
$5.28M +$5.38M +344,015 New
AIC
15
AWM Investment Company
New York
$4.59M +$4.68M +299,147 New
VPC
16
Vestal Point Capital
New York
$3.84M +$3.91M +250,000 New
Citadel Advisors
17
Citadel Advisors
Florida
$2.67M +$2.72M +173,648 New
VM
18
Valor Management
Illinois
$2.41M +$2.46M +157,038 New
BlackRock
19
BlackRock
New York
$2.17M +$2.22M +141,568 New
WP
20
Woodline Partners
California
$1.92M +$1.96M +125,000 New
Millennium Management
21
Millennium Management
New York
$1.83M +$1.87M +119,216 New
FAM
22
Fred Alger Management
New York
$1.81M +$1.85M +118,016 New
Geode Capital Management
23
Geode Capital Management
Massachusetts
$1.32M +$1.35M +86,141 New
BC
24
BIT Capital
Germany
$1.22M +$1.25M +79,562 New
ZP
25
Zimmer Partners
New York
$1.15M +$1.17M +75,000 New
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