|
1
|
Darwin Global Management
St. Helier,
Jersey
|
–
|
-$238M
|
-16,688,636
|
Closed
|
|
|
2
|
Cormorant Asset Management
Boston,
Massachusetts
|
–
|
-$160M
|
-11,231,000
|
Closed
|
|
|
3
|
Paradigm Biocapital Advisors
New York
|
–
|
-$62M
|
-4,352,689
|
Closed
|
|
|
4
|
|
–
|
-$60.4M
|
-4,240,486
|
Closed
|
|
|
5
|
Deep Track Capital
Greenwich,
Connecticut
|
–
|
-$52.8M
|
-3,710,412
|
Closed
|
|
|
6
|
Nextech Invest
Zurich,
Switzerland
|
–
|
-$44.6M
|
-3,129,300
|
Closed
|
|
|
7
|
Balyasny Asset Management
Chicago,
Illinois
|
–
|
-$30.7M
|
-2,154,700
|
Closed
|
|
|
8
|
Logos Global Management
San Francisco,
California
|
–
|
-$29.9M
|
-2,100,000
|
Closed
|
|
|
9
|
|
–
|
-$29.5M
|
-2,070,000
|
Closed
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
–
|
-$29.1M
|
-2,042,212
|
Closed
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-$21M
|
-1,474,258
|
Closed
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$19.9M
|
-1,399,642
|
Closed
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
–
|
-$17.9M
|
-1,255,148
|
Closed
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
–
|
-$15.4M
|
-1,084,247
|
Closed
|
|
|
15
|
WuXi AppTec
Shanghai,
China
|
–
|
-$14.2M
|
-1,000,000
|
Closed
|
|
|
16
|
|
–
|
-$7.14M
|
-501,604
|
Closed
|
|
|
17
|
Ghost Tree Capital
New York
|
–
|
-$6.76M
|
-475,000
|
Closed
|
|
|
18
|
Millennium Management
New York
|
–
|
-$6.16M
|
-432,709
|
Closed
|
|
|
19
|
|
–
|
-$5.69M
|
-399,648
|
Closed
|
|
|
20
|
Ally Bridge Group
New York
|
–
|
-$5.49M
|
-385,383
|
Closed
|
|
|
21
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
–
|
-$4.71M
|
-330,949
|
Closed
|
|
|
22
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
–
|
-$4.27M
|
-300,000
|
Closed
|
|
|
23
|
|
–
|
-$4.22M
|
-296,000
|
Closed
|
|
|
24
|
|
–
|
-$4.21M
|
-295,642
|
Closed
|
|
|
25
|
Schonfeld Strategic Advisors
New York
|
–
|
-$3.76M
|
-263,743
|
Closed
|
|
