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ALMS

Alumis Inc

130 hedge funds and large institutions have $311M invested in Alumis Inc in 2025 Q3 according to their latest regulatory filings, with 33 funds opening new positions, 37 increasing their positions, 31 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

120% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 15

32% more capital invested

Capital invested by funds: $235M → $311M (+$76.2M)

19% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 31

18% more funds holding in top 10

Funds holding in top 10: 1113 (+2)

16% more funds holding

Funds holding: 112130 (+18)

1.08% less ownership

Funds ownership: 81.59%80.51% (-1.1%)

99% less call options, than puts

Call options by funds: $155K | Put options by funds: $10.5M

Holders
130
Holders Change
+18
Holders Change %
+16.07%
% of All Funds
1.71%
Holding in Top 10
13
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+18.18%
% of All Funds
0.17%
New
33
Increased
37
Reduced
31
Closed
15
Calls
$155K
Puts
$10.5M
Net Calls
-$10.3M
Net Calls Change
-$6.37M
Name Holding Trade Value Shares
Change
Change in
Stake
ACMC
1
AyurMaya Capital Management Company
New Hampshire
$60.4M -$4 -1 -0%
FCMV
2
Foresite Capital Management V
California
$23.1M
SB
3
Samsara BioCapital
California
$19.2M
VP
4
venBio Partners
California
$18.4M
FCMV
5
Foresite Capital Management VI
California
$16.9M
BlackRock
6
BlackRock
New York
$16.7M +$71.5K +17,364 +0.4%
Vanguard Group
7
Vanguard Group
Pennsylvania
$16.1M +$2.58M +625,404 +18%
TC
8
Trium Capital
United Kingdom
$12.5M +$1.95M +474,072 +18%
NI
9
Nextech Invest
Switzerland
$11.6M
CAM
10
Cormorant Asset Management
Massachusetts
$8.57M
SOCM
11
SR One Capital Management
Pennsylvania
$7.82M
O
12
OrbiMed
New York
$7.69M
WP
13
Woodline Partners
California
$6.99M +$6.42M +1,558,660 +810%
BBA
14
Baker Bros. Advisors
New York
$6.23M
TCM
15
Tybourne Capital Management
Hong Kong
$5.58M
Geode Capital Management
16
Geode Capital Management
Massachusetts
$5.56M +$929K +225,454 +19%
GA
17
General Atlantic
New York
$5.18M
BCM
18
BML Capital Management
Indiana
$4.83M
TCM
19
Tang Capital Management
California
$4.66M -$3.42M -829,788 -42%
State Street
20
State Street
Massachusetts
$4.4M -$29.7K -7,205 -0.6%
VCIM
21
Velan Capital Investment Management
Georgia
$3.78M -$2.78M -674,163 -42%
YF
22
Yu Fan
$3.15M
UBS Group
23
UBS Group
Switzerland
$3.04M -$1.83M -444,880 -37%
OM
24
Opaleye Management
Massachusetts
$2.65M -$453K -110,000 -14%
OFM
25
Omega Fund Management
Massachusetts
$2.61M

ALMS Hedge Fund Activity: Q3 2025 in Review

130 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Alumis Inc (ALMS) for Q3 2025, worth a combined $311M — up 32% from $235M a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new ALMS positions and 15 closed out — a net gain of 18 holders — while 37 added to existing stakes and 31 trimmed.

The largest buyer was Woodline Partners, adding an estimated $6.42M. The largest seller was Madison Avenue Partners, cutting an estimated $5.87M.

  • 130 institutional investors held Alumis Inc (ALMS) as of Q3 2025, up from 112 in Q2 2025.
  • Funds reported $311M of Alumis Inc stock for Q3 2025, up 32% quarter-over-quarter.
  • 33 funds opened new Alumis Inc positions in Q3 2025 and 15 closed out, a net change of +18 holders.
  • The largest Alumis Inc buyer in Q3 2025 was Woodline Partners, an estimated $6.42M added.
  • The largest Alumis Inc seller in Q3 2025 was Madison Avenue Partners, an estimated $5.87M sold.

Based on aggregated 13F filings for Q3 2025.