Alumis Inc
ALMS
134 hedge funds and large institutions have $771M invested in Alumis Inc in 2025 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 48 increasing their positions, 33 reducing their positions, and 25 closing their positions.
148% more capital invested
Capital invested by funds: $311M → $771M (+$460M)
45% more repeat investments, than reductions
Existing positions increased: 48 | Existing positions reduced: 33
20% more first-time investments, than exits
New positions opened: 30 | Existing positions closed: 25
3% more funds holding
Funds holding: 130 → 134 (+4)
0.84% more ownership
Funds ownership: 80.51% → 81.35% (+0.84%)
8% less funds holding in top 10
Funds holding in top 10: 13 → 12 (-1)
49% less call options, than puts
Call options by funds: $2.01M | Put options by funds: $3.97M
Top Buyers
| 1 |
SVCM
Saturn V Capital Management
Austin,
Texas
|
+$21.9M |
| 2 |
OCA
Octagon Capital Advisors
New York
|
+$17.7M |
| 3 |
MB
MPM BioImpact
Boston,
Massachusetts
|
+$16.8M |
| 4 |
CAM
Cormorant Asset Management
Boston,
Massachusetts
|
+$10.4M |
| 5 |
SB
Samsara BioCapital
Palo Alto,
California
|
+$6.67M |
Top Sellers
| 1 |
TC
Trium Capital
London,
United Kingdom
|
-$15.6M |
| 2 |
WP
Woodline Partners
San Francisco,
California
|
-$6.99M |
| 3 |
O
OrbiMed
New York
|
-$5.75M |
| 4 |
GA
General Atlantic
New York
|
-$5.18M |
| 5 |
BCM
BML Capital Management
Zionsville,
Indiana
|
-$4.83M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
WWM
151
Western Wealth Management
Golden,
Colorado
| – | -$48K | -12,035 | Closed |
|
152
Simplex Trading
Chicago,
Illinois
| – | -$61.7K | -8,837 | Closed |
|
|
QL
153
Quarry LP
New York
| – | -$15.7K | -3,938 | Closed |
|
|
GWSG
154
GPS Wealth Strategies Group
Centennial,
Colorado
| – | -$3.99K | -1,000 | Closed |
|
|
CFG
155
Clayton Financial Group
St. Louis,
Missouri
| – | -$1.92K | -481 | Closed |
|
|
QCG
156
Quadrant Capital Group
Cincinnati,
Ohio
| – | -$451 | -113 | Closed |
|
|
RA
157
Rise Advisors
Rochester,
New York
| – | -$411 | -103 | Closed |
|
|
PS
158
Principal Securities
Des Moines,
Iowa
| – | -$144 | -36 | Closed |
|
|
SIC
159
Salem Investment Counselors
Winston Salem,
North Carolina
| – | -$80 | -20 | Closed |
|
ALMS Hedge Fund Activity: Q4 2025 in Review
134 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Alumis Inc (ALMS) for Q4 2025, worth a combined $771M — up 148% from $311M a quarter earlier.
Buyers outnumbered sellers: 30 funds opened new ALMS positions and 25 closed out — a net gain of 5 holders — while 48 added to existing stakes and 33 trimmed.
The largest buyer was Saturn V Capital Management, opening a new position worth an estimated $21.9M. The largest seller was Trium Capital, cutting an estimated $15.6M.
- 134 institutional investors held Alumis Inc (ALMS) as of Q4 2025, up from 130 in Q3 2025.
- Funds reported $771M of Alumis Inc stock for Q4 2025, up 148% quarter-over-quarter.
- 30 funds opened new Alumis Inc positions in Q4 2025 and 25 closed out, a net change of +5 holders.
- The largest Alumis Inc buyer in Q4 2025 was Saturn V Capital Management, an estimated $21.9M added.
- The largest Alumis Inc seller in Q4 2025 was Trium Capital, an estimated $15.6M sold.
Based on aggregated 13F filings for Q4 2025.