|
1
|
Capital World Investors
Los Angeles,
California
|
$747M
|
+$9.5M
|
+75,190
|
+1%
|
|
|
2
|
Capital Research Global Investors
Los Angeles,
California
|
$729M
|
+$1.08M
|
+8,563
|
+0.1%
|
|
|
3
|
RiverVest Venture Management
St. Louis,
Missouri
|
$561M
|
-$109M
|
-862,574
|
-15%
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$397M
|
+$185M
|
+1,466,218
|
+74%
|
|
|
5
|
|
$393M
|
-$13.9M
|
-109,983
|
-3%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$377M
|
+$33.4M
|
+264,185
|
+9%
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$278M
|
-$31.3M
|
-248,033
|
-9%
|
|
|
8
|
Capital International Investors
Los Angeles,
California
|
$261M
|
-$78.9M
|
-624,802
|
-22%
|
|
|
9
|
NEA Management Company
Timonium,
Maryland
|
$248M
|
–
|
–
|
–
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$102M
|
-$3.61M
|
-28,565
|
-3%
|
|
|
11
|
Baker Bros. Advisors
New York
|
$80.7M
|
-$1.41M
|
-11,200
|
-2%
|
|
|
12
|
Janus Henderson Group
London,
|
$62.8M
|
+$69.1M
|
+547,434
|
New
|
|
|
13
|
AllianceBernstein
Nashville,
Tennessee
|
$58.6M
|
+$1.65M
|
+13,076
|
+3%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$57.9M
|
+$4.7M
|
+37,222
|
+8%
|
|
|
15
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$44.7M
|
-$11.1M
|
-87,697
|
-18%
|
|
|
16
|
Fidelity Investments
Boston,
Massachusetts
|
$41.4M
|
-$15.9M
|
-125,930
|
-26%
|
|
|
17
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$40.4M
|
+$2.43M
|
+19,267
|
+6%
|
|
|
18
|
Eventide Asset Management
Boston,
Massachusetts
|
$36.4M
|
–
|
–
|
–
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$35.2M
|
-$1.41M
|
-11,143
|
-4%
|
|
|
20
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$35.1M
|
-$4.52M
|
-35,794
|
-10%
|
|
|
21
|
|
$26.6M
|
+$10.2M
|
+80,435
|
+53%
|
|
|
22
|
Charles Schwab
San Francisco,
California
|
$24.8M
|
+$978K
|
+7,740
|
+4%
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
$18.8M
|
+$4.13M
|
+32,708
|
+25%
|
|
|
24
|
Capital International Inc
Los Angeles,
California
|
$18.1M
|
-$2.13M
|
-16,882
|
-10%
|
|
|
25
|
|
$17.6M
|
+$10.3M
|
+81,200
|
+113%
|
|
