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Akebia Therapeutics

177 hedge funds and large institutions have $338M invested in Akebia Therapeutics in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 66 increasing their positions, 40 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

122% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 18

75% more call options, than puts

Call options by funds: $2.11M | Put options by funds: $1.21M

65% more repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 40

13% more funds holding

Funds holding: 157177 (+20)

5.42% more ownership

Funds ownership: 41.23%46.64% (+5.4%)

14% less capital invested

Capital invested by funds: $394M → $338M (-$56.4M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
177
Holders Change
+20
Holders Change %
+12.74%
% of All Funds
2.32%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
40
Increased
66
Reduced
40
Closed
18
Calls
$2.11M
Puts
$1.21M
Net Calls
+$902K
Net Calls Change
+$215K
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$51.3M +$1.41M +423,097 +2%
Vanguard Group
2
Vanguard Group
Pennsylvania
$42.4M +$3.11M +936,042 +6%
State Street
3
State Street
Massachusetts
$32.3M +$12.8M +3,847,616 +48%
Geode Capital Management
4
Geode Capital Management
Massachusetts
$16.9M +$368K +110,493 +2%
Morgan Stanley
5
Morgan Stanley
New York
$11.8M -$3.41M -1,024,453 -19%
Renaissance Technologies
6
Renaissance Technologies
New York
$10.8M -$804K -241,700 -6%
UBS Group
7
UBS Group
Switzerland
$9.95M +$10M +3,006,771 +470%
Qube Research & Technologies (QRT)
8
Qube Research & Technologies (QRT)
United Kingdom
$8.75M +$4.96M +1,491,640 +87%
Citadel Advisors
9
Citadel Advisors
Florida
$8.7M +$2.89M +868,536 +37%
MB
10
MPM BioImpact
Massachusetts
$7.89M
Millennium Management
11
Millennium Management
New York
$7.8M +$2.31M +693,738 +32%
Franklin Resources
12
Franklin Resources
California
$7.32M +$42.5K +12,776 +0.5%
Northern Trust
13
Northern Trust
Illinois
$6.79M +$1.17M +351,291 +16%
AAA
14
Affinity Asset Advisors
New York
$6.69M +$1.66M +500,000 +26%
Invesco
15
Invesco
Georgia
$6.55M +$6.71M +2,018,547 +528%
N
16
Nuveen
North Carolina
$6.28M -$1.35M -407,299 -15%
Charles Schwab
17
Charles Schwab
California
$5.92M +$4.73M +1,421,266 +190%
Acadian Asset Management
18
Acadian Asset Management
Massachusetts
$5.86M +$2.65M +797,766 +59%
NCM
19
Nantahala Capital Management
Connecticut
$5.46M
Citigroup
20
Citigroup
New York
$5.23M +$5.93M +1,782,162 +1,325%
Bank of America
21
Bank of America
North Carolina
$4.88M +$2.26M +678,020 +61%
Goldman Sachs
22
Goldman Sachs
New York
$4.83M -$7.21M -2,166,189 -55%
Dimensional Fund Advisors
23
Dimensional Fund Advisors
Texas
$4.82M +$2.94M +884,590 +100%
Barclays
24
Barclays
United Kingdom
$3.22M +$651K +195,721 +20%
Connor, Clark & Lunn Investment Management (CC&L)
25
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.79M -$533K -160,091 -14%

AKBA Hedge Fund Activity: Q3 2025 in Review

177 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Akebia Therapeutics (AKBA) for Q3 2025, worth a combined $338M — down 14% from $394M a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new AKBA positions and 18 closed out — a net gain of 22 holders — while 66 added to existing stakes and 40 trimmed.

The largest buyer was State Street, adding an estimated $12.8M. The largest seller was Great Point Partners, exiting entirely with an estimated $7.23M sold.

  • 177 institutional investors held Akebia Therapeutics (AKBA) as of Q3 2025, up from 157 in Q2 2025.
  • Funds reported $338M of Akebia Therapeutics stock for Q3 2025, down 14% quarter-over-quarter.
  • 40 funds opened new Akebia Therapeutics positions in Q3 2025 and 18 closed out, a net change of +22 holders.
  • The largest Akebia Therapeutics buyer in Q3 2025 was State Street, an estimated $12.8M added.
  • The largest Akebia Therapeutics seller in Q3 2025 was Great Point Partners, an estimated $7.23M sold.

Based on aggregated 13F filings for Q3 2025.