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Akebia Therapeutics
AKBA

177 hedge funds and large institutions have $338M invested in Akebia Therapeutics in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 66 increasing their positions, 40 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

122% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 18

75% more call options, than puts

Call options by funds: $2.11M | Put options by funds: $1.21M

65% more repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 40

13% more funds holding

Funds holding: 157 → 177 (+20)

5.42% more ownership

Funds ownership: 41.23% → 46.64% (+5.4%)

14% less capital invested

Capital invested by funds: $394M → $338M (-$56.4M)

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders
177
Holders Change
+20
Holders Change %
+12.74%
% of All Funds
2.32%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
40
Increased
66
Reduced
40
Closed
18
Calls
$2.11M
Puts
$1.21M
Net Calls
+$902K
Net Calls Change
+$215K

Top Buyers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
+$12.8M
2
UBS Group
UBS Group
Switzerland
+$10M
3
Invesco
Invesco
Georgia
+$6.71M
4
Citigroup
Citigroup
New York
+$5.93M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
+$4.96M

Top Sellers

Rank Fund Capital Flow
1
GPP
Great Point Partners
Connecticut
-$7.23M
2
Goldman Sachs
Goldman Sachs
New York
-$7.21M
3
EI
EAM Investors
California
-$5.29M
4
WP
Woodline Partners
California
-$3.64M
5
Morgan Stanley
Morgan Stanley
New York
-$3.41M
Name Holding Trade Value Shares
Change 		Change in
Stake
Nisa Investment Advisors
151
Nisa Investment Advisors
Missouri
$8.25K – – –
CIAM
152
Caitong International Asset Management
Hong Kong
$7.06K +$7.77K +2,336 +938%
GWP
153
Gen-Wealth Partners
Michigan
$6.26K +$7.63K +2,295 New
Optiver Holding
154
Optiver Holding
Netherlands
$5.96K +$7.26K +2,184 New
AWM
155
Activest Wealth Management
Florida
$5.46K – – –
Rockefeller Capital Management
156
Rockefeller Capital Management
New York
$5.11K +$6.22K +1,871 New
BNP Paribas Asset Management
157
BNP Paribas Asset Management
France
$5K +$6.43K +1,934 New
Comerica Bank
158
Comerica Bank
Texas
$3.59K – – –
CA
159
Clearstead Advisors
Ohio
$2.29K – – –
AF
160
Allworth Financial
California
$2.07K +$37 +11 +1%
TC
161
Truvestments Capital
Florida
$2.06K – – –
Northwestern Mutual Wealth Management
162
Northwestern Mutual Wealth Management
Wisconsin
$2.04K +$2.49K +748 New
EP
163
Essential Partners
California
$1.5K +$43 +13 +2%
Jones Financial Companies
164
Jones Financial Companies
Missouri
$1.36K – – –
EWA
165
EverSource Wealth Advisors
Alabama
$1.28K -$213 -64 -12%
PFBT
166
Parkside Financial Bank & Trust
Missouri
$1.16K +$602 +181 +74%
FFA
167
Farther Finance Advisors
California
$1.13K – – –
RIL
168
Rothschild Investment LLC
Illinois
$1.06K -$665 -200 -34%
CAL
169
Capital Advisors Ltd
Ohio
$1K – – –
TWC
170
TD Waterhouse Canada
Ontario, Canada
$876 – – –
PWA
171
Physician Wealth Advisors
Utah
$743 – – –
SAM
172
Smartleaf Asset Management
Massachusetts
$490 +$602 +181 New
FDCDDQ
173
Federation des caisses Desjardins du Quebec
Quebec, Canada
$410 – – –
SS
174
Sunbelt Securities
Texas
$227 +$276 +83 New
TWD
175
True Wealth Design
Ohio
$159 – – –
4 5 6
7
8

AKBA Hedge Fund Activity: Q3 2025 in Review

177 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Akebia Therapeutics (AKBA) for Q3 2025, worth a combined $338M — down 14% from $394M a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new AKBA positions and 18 closed out — a net gain of 22 holders — while 66 added to existing stakes and 40 trimmed.

The largest buyer was State Street, adding an estimated $12.8M. The largest seller was Great Point Partners, exiting entirely with an estimated $7.23M sold.

  • 177 institutional investors held Akebia Therapeutics (AKBA) as of Q3 2025, up from 157 in Q2 2025.
  • Funds reported $338M of Akebia Therapeutics stock for Q3 2025, down 14% quarter-over-quarter.
  • 40 funds opened new Akebia Therapeutics positions in Q3 2025 and 18 closed out, a net change of +22 holders.
  • The largest Akebia Therapeutics buyer in Q3 2025 was State Street, an estimated $12.8M added.
  • The largest Akebia Therapeutics seller in Q3 2025 was Great Point Partners, an estimated $7.23M sold.

Based on aggregated 13F filings for Q3 2025.