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Akebia Therapeutics
AKBA

177 hedge funds and large institutions have $338M invested in Akebia Therapeutics in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 66 increasing their positions, 40 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

122% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 18

75% more call options, than puts

Call options by funds: $2.11M | Put options by funds: $1.21M

65% more repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 40

13% more funds holding

Funds holding: 157 → 177 (+20)

5.42% more ownership

Funds ownership: 41.23% → 46.64% (+5.4%)

14% less capital invested

Capital invested by funds: $394M → $338M (-$56.4M)

100% less funds holding in top 10

Funds holding in top 10: 1 → 0 (-1)

Holders
177
Holders Change
+20
Holders Change %
+12.74%
% of All Funds
2.32%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
40
Increased
66
Reduced
40
Closed
18
Calls
$2.11M
Puts
$1.21M
Net Calls
+$902K
Net Calls Change
+$215K

Top Buyers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
+$12.8M
2
UBS Group
UBS Group
Switzerland
+$10M
3
Invesco
Invesco
Georgia
+$6.71M
4
Citigroup
Citigroup
New York
+$5.93M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
+$4.96M

Top Sellers

Rank Fund Capital Flow
1
GPP
Great Point Partners
Connecticut
-$7.23M
2
Goldman Sachs
Goldman Sachs
New York
-$7.21M
3
EI
EAM Investors
California
-$5.29M
4
WP
Woodline Partners
California
-$3.64M
5
Morgan Stanley
Morgan Stanley
New York
-$3.41M
Name Holding Trade Value Shares
Change 		Change in
Stake
JP Morgan Chase
26
JP Morgan Chase
New York
$2.71M -$2.19M -658,565 -40%
Fidelity Investments
27
Fidelity Investments
Massachusetts
$2.49M +$325K +97,839 +12%
Wellington Management Group
28
Wellington Management Group
Massachusetts
$2.37M +$579K +174,076 +25%
BNP Paribas Financial Markets
29
BNP Paribas Financial Markets
France
$2.34M +$1.12M +337,912 +65%
Squarepoint
30
Squarepoint
New York
$2.13M +$2.05M +617,337 +383%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$1.85M +$212K +63,641 +10%
Jacobs Levy Equity Management
32
Jacobs Levy Equity Management
New Jersey
$1.81M -$1.81M -542,598 -45%
Federated Hermes
33
Federated Hermes
Pennsylvania
$1.75M +$73.4K +22,054 +4%
Swiss National Bank
34
Swiss National Bank
Switzerland
$1.39M +$1.69M +509,300 New
ACM
35
Aquatic Capital Management
Illinois
$1.38M +$1.52M +458,276 +942%
Susquehanna International Group
36
Susquehanna International Group
Pennsylvania
$1.34M -$995K -299,018 -38%
Rafferty Asset Management
37
Rafferty Asset Management
New York
$1.32M +$758K +227,915 +90%
AQR Capital Management
38
AQR Capital Management
Connecticut
$1.21M +$55K +16,523 +4%
Assenagon Asset Management
39
Assenagon Asset Management
Luxembourg
$1.17M +$1.42M +426,766 New
RhumbLine Advisers
40
RhumbLine Advisers
Massachusetts
$979K -$21.2K -6,364 -2%
JF
41
Jump Financial
Illinois
$971K +$1.18M +355,843 New
American Century Companies
42
American Century Companies
Missouri
$954K +$863K +259,343 +288%
UBS AM
43
UBS AM
Illinois
$893K +$997K +299,654 +1,097%
Victory Capital Management
44
Victory Capital Management
Texas
$782K +$853K +256,353 +854%
Creative Planning
45
Creative Planning
Kansas
$771K -$2.78K -835 -0.3%
Prudential Financial
46
Prudential Financial
New Jersey
$766K -$448K -134,585 -32%
Mackenzie Financial
47
Mackenzie Financial
Ontario, Canada
$724K +$55.5K +16,678 +7%
California State Teachers Retirement System (CalSTRS)
48
California State Teachers Retirement System (CalSTRS)
California
$676K +$774K +232,627 +1,543%
Legal & General Group
49
Legal & General Group
United Kingdom
$670K +$738K +221,972 +954%
AllianceBernstein
50
AllianceBernstein
Tennessee
$652K – – –
1
2
3 4 5

AKBA Hedge Fund Activity: Q3 2025 in Review

177 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Akebia Therapeutics (AKBA) for Q3 2025, worth a combined $338M — down 14% from $394M a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new AKBA positions and 18 closed out — a net gain of 22 holders — while 66 added to existing stakes and 40 trimmed.

The largest buyer was State Street, adding an estimated $12.8M. The largest seller was Great Point Partners, exiting entirely with an estimated $7.23M sold.

  • 177 institutional investors held Akebia Therapeutics (AKBA) as of Q3 2025, up from 157 in Q2 2025.
  • Funds reported $338M of Akebia Therapeutics stock for Q3 2025, down 14% quarter-over-quarter.
  • 40 funds opened new Akebia Therapeutics positions in Q3 2025 and 18 closed out, a net change of +22 holders.
  • The largest Akebia Therapeutics buyer in Q3 2025 was State Street, an estimated $12.8M added.
  • The largest Akebia Therapeutics seller in Q3 2025 was Great Point Partners, an estimated $7.23M sold.

Based on aggregated 13F filings for Q3 2025.