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Akebia Therapeutics
AKBA

157 hedge funds and large institutions have $394M invested in Akebia Therapeutics in 2025 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 78 increasing their positions, 22 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

255% more repeat investments, than reductions

Existing positions increased: 78 | Existing positions reduced: 22

94% more capital invested

Capital invested by funds: $203M → $394M (+$191M)

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

46% more call options, than puts

Call options by funds: $2.19M | Put options by funds: $1.51M

10% more funds holding

Funds holding: 143 → 157 (+14)

4.67% more ownership

Funds ownership: 36.56% → 41.23% (+4.7%)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

Holders
157
Holders Change
+14
Holders Change %
+9.79%
% of All Funds
2.07%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
32
Increased
78
Reduced
22
Closed
18
Calls
$2.19M
Puts
$1.51M
Net Calls
+$687K
Net Calls Change
+$1.22M

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$8.36M
2
MB
MPM BioImpact
Massachusetts
+$7.94M
3
Morgan Stanley
Morgan Stanley
New York
+$7.3M
4
N
Nuveen
North Carolina
+$6.48M
5
Vanguard Group
Vanguard Group
Pennsylvania
+$5.29M

Top Sellers

Rank Fund Capital Flow
1
GPP
Great Point Partners
Connecticut
-$8.21M
2
ACM
AIGH Capital Management
Maryland
-$5.62M
3
WP
Woodline Partners
California
-$4.08M
4
Citadel Advisors
Citadel Advisors
Florida
-$3.65M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$3.4M
Name Holding Trade Value Shares
Change 		Change in
Stake
Dimensional Fund Advisors
26
Dimensional Fund Advisors
Texas
$3.21M +$953K +346,670 +65%
Fidelity Investments
27
Fidelity Investments
Massachusetts
$2.96M -$161K -58,502 -7%
Susquehanna International Group
28
Susquehanna International Group
Pennsylvania
$2.88M +$286K +104,073 +15%
Charles Schwab
29
Charles Schwab
California
$2.73M +$346K +126,101 +20%
Wellington Management Group
30
Wellington Management Group
Massachusetts
$2.53M +$80.1K +29,161 +4%
UBS Group
31
UBS Group
Switzerland
$2.33M +$129K +47,052 +8%
Federated Hermes
32
Federated Hermes
Pennsylvania
$2.25M -$814K -296,131 -32%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$2.24M +$335K +122,008 +25%
BNP Paribas Financial Markets
34
BNP Paribas Financial Markets
France
$1.9M +$1.3M +472,855 +990%
AQR Capital Management
35
AQR Capital Management
Connecticut
$1.55M +$684K +248,988 +141%
Prudential Financial
36
Prudential Financial
New Jersey
$1.51M +$963K +350,504 +542%
Invesco
37
Invesco
Georgia
$1.39M +$334K +121,607 +47%
RhumbLine Advisers
38
RhumbLine Advisers
Massachusetts
$1.33M +$228K +82,969 +29%
ECM
39
ExodusPoint Capital Management
New York
$1.05M +$796K +289,528 New
Creative Planning
40
Creative Planning
Kansas
$1.03M +$147K +53,660 +23%
Rafferty Asset Management
41
Rafferty Asset Management
New York
$924K +$130K +47,324 +23%
Mackenzie Financial
42
Mackenzie Financial
Ontario, Canada
$905K +$30.3K +11,044 +5%
AllianceBernstein
43
AllianceBernstein
Tennessee
$870K +$513K +186,660 +357%
D.E. Shaw & Co
44
D.E. Shaw & Co
New York
$797K +$401K +145,928 +199%
Walleye Capital
45
Walleye Capital
New York
$782K +$590K +214,817 New
PAM
46
Panagora Asset Management
Massachusetts
$765K +$578K +210,205 New
SC
47
Sapient Capital
Indiana
$728K – – –
Simplex Trading
48
Simplex Trading
Illinois
$702K +$150K +54,564 +39%
LP
49
Longaeva Partners
Illinois
$698K -$847K -308,309 -62%
SEI Investments
50
SEI Investments
Pennsylvania
$696K +$44.5K +16,200 +9%
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AKBA Hedge Fund Activity: Q2 2025 in Review

157 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Akebia Therapeutics (AKBA) for Q2 2025, worth a combined $394M — up 94% from $203M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new AKBA positions and 18 closed out — a net gain of 14 holders — while 78 added to existing stakes and 22 trimmed.

The largest buyer was BlackRock, adding an estimated $8.36M. The largest seller was Great Point Partners, cutting an estimated $8.21M.

  • 157 institutional investors held Akebia Therapeutics (AKBA) as of Q2 2025, up from 143 in Q1 2025.
  • Funds reported $394M of Akebia Therapeutics stock for Q2 2025, up 94% quarter-over-quarter.
  • 32 funds opened new Akebia Therapeutics positions in Q2 2025 and 18 closed out, a net change of +14 holders.
  • The largest Akebia Therapeutics buyer in Q2 2025 was BlackRock, an estimated $8.36M added.
  • The largest Akebia Therapeutics seller in Q2 2025 was Great Point Partners, an estimated $8.21M sold.

Based on aggregated 13F filings for Q2 2025.