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Agios Pharmaceuticals
AGIO

Overview Fund Activity

213 hedge funds and large institutions have $2.05B invested in Agios Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 87 increasing their positions, 76 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
213
Holders Change
-5
Holders Change %
-2.29%
% of All Funds
2.86%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
22
Increased
87
Reduced
76
Closed
25
Calls
$11.2M
Puts
$8.65M
Net Calls
+$2.57M
Net Calls Change
+$3.05M

Top Buyers

1
PBA
Paradigm Biocapital Advisors
New York
+$38M
2
TCM
TCG Crossover Management
California
+$23.2M
3
RSCM
Rock Springs Capital Management
Maryland
+$21.5M
4
Wellington Management Group
Wellington Management Group
Massachusetts
+$13.2M
5
CP
Caligan Partners
New York
+$12.3M

Top Sellers

1
PCH
Polar Capital Holdings
United Kingdom
-$29.4M
2
AC
Armistice Capital
New York
-$29.3M
3
State Street
State Street
Massachusetts
-$16.6M
4
BlackRock
BlackRock
New York
-$9.15M
5
ACH
ArrowMark Colorado Holdings
Colorado
-$5.62M
Name Holding Trade Value Shares
Change 		Shares
Change %
PA
201
Parallel Advisors
California
$399 -$16.4K -492 -98%
TWD
202
True Wealth Design
Ohio
$300 +$133 +4 +80%
SPIA
203
Steward Partners Investment Advisory
New York
$299 – – –
FFO
204
Fortitude Family Office
Arizona
$166 +$166 +5 New
RAM
205
Riggs Asset Management
Pennsylvania
$100 -$1.27K -38 -93%
SS
206
SBI Securities
Japan
$100 – – –
RWM
207
Rialto Wealth Management
New York
$67 +$67 +2 New
BHWM
208
Bay Harbor Wealth Management
Maryland
$66 +$33 +1 +100%
DPW
209
DiNuzzo Private Wealth
Pennsylvania
$34 -$34 -1 -50%
SIC
210
SJS Investment Consulting
Ohio
$34 -$34 -1 -50%
HIA
211
HFM Investment Advisors
New Jersey
$33 – – –
Jones Financial Companies
212
Jones Financial Companies
Missouri
$33 +$33 +1 New
PCH
213
Polar Capital Holdings
United Kingdom
– -$29.4M -1,002,036 Closed
CCM
214
Cutter Capital Management
New York
– -$6.9M -235,350 Closed
Walleye Capital
215
Walleye Capital
New York
– -$4.41M -150,511 Closed
GCP
216
GSA Capital Partners
United Kingdom
– -$1.2M -41,029 Closed
Squarepoint
217
Squarepoint
New York
– -$1.11M -37,920 Closed
CM
218
Capula Management
Cayman Islands
– -$872K -29,749 Closed
Verition Fund Management
219
Verition Fund Management
Connecticut
– -$813K -27,753 Closed
CF
220
Corebridge Financial
Texas
– -$811K -27,688 Closed
AIM
221
Allen Investment Management
New York
– -$638K -21,781 Closed
XT
222
XTX Topco
Cayman Islands
– -$404K -13,801 Closed
Group One Trading
223
Group One Trading
Illinois
– -$386K -13,188 Closed
Man Group
224
Man Group
United Kingdom
– -$341K -11,622 Closed
CFM
225
Catalyst Funds Management
Australia
– -$328K -11,200 Closed
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9
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