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Agios Pharmaceuticals

232 hedge funds and large institutions have $2.12B invested in Agios Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 82 increasing their positions, 81 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed

620% more call options, than puts

Call options by funds: $127M | Put options by funds: $17.6M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

27% more capital invested

Capital invested by funds: $1.67B → $2.12B (+$452M)

2.54% more ownership

Funds ownership: 105.05%107.59% (+2.5%)

1% more repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 81

0% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 36

2% less funds holding

Funds holding: 237232 (-5)

Holders
232
Holders Change
-5
Holders Change %
-2.11%
% of All Funds
2.86%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
36
Increased
82
Reduced
81
Closed
36
Calls
$127M
Puts
$17.6M
Net Calls
+$109M
Net Calls Change
+$22M
Name Holding Trade Value Shares
Change
Change in
Stake
BC
176
Bayforest Capital
United Kingdom
$95.2K +$79.8K +2,815 New
ECSS
177
Eurizon Capital SGR SpA
$78.8K
KBC Group
178
KBC Group
Belgium
$70K -$26.8K -947 -31%
SCM
179
Sterling Capital Management
North Carolina
$63.3K -$40K -1,412 -43%
Osaic Holdings
180
Osaic Holdings
Arizona
$60.4K +$1.11K +39 +2%
AssetMark Inc
181
AssetMark Inc
California
$44.6K
GFM
182
GF Fund Management
China
$44.3K +$4.68K +165 +14%
Carson Wealth (CWM LLC)
183
Carson Wealth (CWM LLC)
Nebraska
$43.3K +$22.6K +797 +165%
Los Angeles Capital Management
184
Los Angeles Capital Management
California
$32.1K +$18.4K +650 +217%
GI
185
GAMMA Investing
California
$23.2K +$14.6K +516 +302%
FHC
186
First Horizon Corporation
Tennessee
$21.8K -$69.5K -2,452 -79%
US Bancorp
187
US Bancorp
Minnesota
$18.3K +$936 +33 +6%
Nisa Investment Advisors
188
Nisa Investment Advisors
Missouri
$17.4K +$6.18K +218 +74%
CHC
189
City Holding Co
West Virginia
$16.9K
KAS
190
Kemnay Advisory Services
New York
$16.1K +$13.5K +477 New
VCM
191
Versant Capital Management
Arizona
$14.1K +$9.24K +326 +354%
SSG
192
Summit Securities Group
New York
$13.8K +$11.6K +408 New
S
193
SignatureFD
Georgia
$13.5K
SAM
194
Smartleaf Asset Management
Massachusetts
$12.6K -$1.02K -36 -8%
ASN
195
Advisory Services Network
Georgia
$11.8K +$9.92K +350 New
TSMHT
196
Thurston Springer Miller Herd & Titak
Indiana
$8.15K
BIA
197
Bell Investment Advisors
California
$8.02K -$1.25K -44 -16%
Fifth Third Bancorp
198
Fifth Third Bancorp
Ohio
$7.09K +$5.93K +209 New
FFA
199
Farther Finance Advisors
California
$6.91K +$1.45K +51 +34%
HIM
200
Hillsdale Investment Management
Ontario, Canada
$6.77K

AGIO Hedge Fund Activity: Q1 2026 in Review

232 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Agios Pharmaceuticals (AGIO) for Q1 2026, worth a combined $2.12B — up 27% from $1.67B a quarter earlier.

Fund positioning in AGIO was balanced in Q1 2026: 36 funds opened new positions, 36 closed out, 82 added to existing stakes and 81 trimmed.

The largest buyer was Lynx1 Capital Management, adding an estimated $71.8M. The largest seller was TCG Crossover Management, exiting entirely with an estimated $32.2M sold.

  • 232 institutional investors held Agios Pharmaceuticals (AGIO) as of Q1 2026, down from 237 in Q4 2025.
  • Funds reported $2.12B of Agios Pharmaceuticals stock for Q1 2026, up 27% quarter-over-quarter.
  • 36 funds opened new Agios Pharmaceuticals positions in Q1 2026 and 36 closed out, a net change of 0 holders.
  • The largest Agios Pharmaceuticals buyer in Q1 2026 was Lynx1 Capital Management, an estimated $71.8M added.
  • The largest Agios Pharmaceuticals seller in Q1 2026 was TCG Crossover Management, an estimated $32.2M sold.

Based on aggregated 13F filings for Q1 2026.