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Agios Pharmaceuticals

232 hedge funds and large institutions have $2.12B invested in Agios Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 82 increasing their positions, 81 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed

620% more call options, than puts

Call options by funds: $127M | Put options by funds: $17.6M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

27% more capital invested

Capital invested by funds: $1.67B → $2.12B (+$452M)

2.54% more ownership

Funds ownership: 105.05%107.59% (+2.5%)

1% more repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 81

0% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 36

2% less funds holding

Funds holding: 237232 (-5)

Holders
232
Holders Change
-5
Holders Change %
-2.11%
% of All Funds
2.86%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
36
Increased
82
Reduced
81
Closed
36
Calls
$127M
Puts
$17.6M
Net Calls
+$109M
Net Calls Change
+$22M
Name Holding Trade Value Shares
Change
Change in
Stake
Canada Life
151
Canada Life
Manitoba, Canada
$362K +$7K +247 +2%
CUAMC
152
China Universal Asset Management Company
China
$352K +$25.4K +896 +9%
VOYA Investment Management
153
VOYA Investment Management
Georgia
$338K -$3.91K -138 -1%
VCM
154
Voleon Capital Management
California
$327K +$274K +9,679 New
Nomura Holdings
155
Nomura Holdings
Japan
$310K -$90.1K -3,179 -26%
Fidelity Investments
156
Fidelity Investments
Massachusetts
$309K -$431K -15,213 -63%
Prudential Financial
157
Prudential Financial
New Jersey
$306K -$2.04M -72,010 -89%
IC
158
Inscription Capital
Texas
$291K
TRCT
159
Tower Research Capital (TRC)
New York
$285K +$50.6K +1,783 +27%
GSC
160
Ground Swell Capital
South Carolina
$282K +$237K +8,347 New
Franklin Resources
161
Franklin Resources
California
$280K +$235K +8,287 New
FT
162
Fiduciary Trust
Massachusetts
$279K
PP
163
PDT Partners
New York
$254K +$213K +7,500 New
Teacher Retirement System of Texas
164
Teacher Retirement System of Texas
Texas
$241K -$29.5K -1,040 -13%
Public Employees Retirement Association of Colorado
165
Public Employees Retirement Association of Colorado
Colorado
$230K
SAI
166
Savvy Advisors Inc
New York
$230K +$193K +6,794 New
Ensign Peak Advisors
167
Ensign Peak Advisors
Utah
$222K
BC
168
Bridgefront Capital
Texas
$222K -$173K -6,098 -48%
MF
169
Magnetar Financial
Illinois
$201K +$168K +5,936 New
Acadian Asset Management
170
Acadian Asset Management
Massachusetts
$196K +$166K +5,859 New
SOADOR
171
State of Alaska Department of Revenue
Alaska
$169K
PNC Financial Services Group
172
PNC Financial Services Group
Pennsylvania
$167K +$6.52K +230 +5%
AIP
173
Ameritas Investment Partners
Nebraska
$160K
Jones Financial Companies
174
Jones Financial Companies
Missouri
$119K +$115K +4,043 +404,300%
Mirae Asset Global Investments
175
Mirae Asset Global Investments
South Korea
$103K +$6.29K +222 +8%

AGIO Hedge Fund Activity: Q1 2026 in Review

232 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Agios Pharmaceuticals (AGIO) for Q1 2026, worth a combined $2.12B — up 27% from $1.67B a quarter earlier.

Fund positioning in AGIO was balanced in Q1 2026: 36 funds opened new positions, 36 closed out, 82 added to existing stakes and 81 trimmed.

The largest buyer was Lynx1 Capital Management, adding an estimated $71.8M. The largest seller was TCG Crossover Management, exiting entirely with an estimated $32.2M sold.

  • 232 institutional investors held Agios Pharmaceuticals (AGIO) as of Q1 2026, down from 237 in Q4 2025.
  • Funds reported $2.12B of Agios Pharmaceuticals stock for Q1 2026, up 27% quarter-over-quarter.
  • 36 funds opened new Agios Pharmaceuticals positions in Q1 2026 and 36 closed out, a net change of 0 holders.
  • The largest Agios Pharmaceuticals buyer in Q1 2026 was Lynx1 Capital Management, an estimated $71.8M added.
  • The largest Agios Pharmaceuticals seller in Q1 2026 was TCG Crossover Management, an estimated $32.2M sold.

Based on aggregated 13F filings for Q1 2026.