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Agios Pharmaceuticals

237 hedge funds and large institutions have $1.67B invested in Agios Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 65 funds opening new positions, 79 increasing their positions, 70 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $133M | Put options by funds: $45.6M

48% more first-time investments, than exits

New positions opened: 65 | Existing positions closed: 44

13% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 70

8% more funds holding

Funds holding: 220237 (+17)

4.24% less ownership

Funds ownership: 109.29%105.05% (-4.2%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

35% less capital invested

Capital invested by funds: $2.55B → $1.67B (-$879M)

Holders
237
Holders Change
+17
Holders Change %
+7.73%
% of All Funds
2.88%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
65
Increased
79
Reduced
70
Closed
44
Calls
$133M
Puts
$45.6M
Net Calls
+$87.2M
Net Calls Change
+$80.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Nomura Holdings
151
Nomura Holdings
Japan
$336K +$433K +12,355 New
A
152
AlphaQuest
New York
$326K +$230K +6,552 +121%
PFCS
153
Pale Fire Capital SE
Czech Republic
$323K +$416K +11,850 New
KK
154
KLP Kapitalforvaltning
Norway
$321K
GFA
155
Gallagher Fiduciary Advisors
Illinois
$306K -$526 -15 -0.1%
Canada Life
156
Canada Life
Manitoba, Canada
$284K -$347K -9,888 -49%
Creative Planning
157
Creative Planning
Kansas
$282K -$96.4K -2,749 -21%
Capstone Investment Advisors
158
Capstone Investment Advisors
New York
$282K +$363K +10,355 New
VOYA Investment Management
159
VOYA Investment Management
Georgia
$276K
SO
160
STRS Ohio
Ohio
$272K +$351K +10,000 New
CUAMC
161
China Universal Asset Management Company
China
$259K -$23.9K -682 -7%
TSS
162
Two Sigma Securities
New York
$250K +$323K +9,198 New
DT
163
Diversified Trust
Tennessee
$249K +$321K +9,162 New
IC
164
Inscription Capital
Texas
$234K +$302K +8,595 New
FT
165
Fiduciary Trust
Massachusetts
$224K +$98K +2,793 +51%
CCIA
166
Campbell & Co Investment Adviser
Maryland
$224K +$289K +8,226 New
Teacher Retirement System of Texas
167
Teacher Retirement System of Texas
Texas
$222K -$187K -5,317 -39%
GAM
168
Griffin Asset Management
New York
$201K +$259K +7,382 New
Public Employees Retirement Association of Colorado
169
Public Employees Retirement Association of Colorado
Colorado
$185K
CIAM
170
Caitong International Asset Management
Hong Kong
$183K +$236K +6,740 New
TRCT
171
Tower Research Capital (TRC)
New York
$181K +$185K +5,277 +389%
Ensign Peak Advisors
172
Ensign Peak Advisors
Utah
$179K -$212K -6,050 -48%
Simplex Trading
173
Simplex Trading
Illinois
$169K +$218K +6,209 New
CIM
174
Contravisory Investment Management
Massachusetts
$168K +$217K +6,189 New
SOADOR
175
State of Alaska Department of Revenue
Alaska
$136K +$175K +5,000 New