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Agios Pharmaceuticals
AGIO

Overview Fund Activity

213 hedge funds and large institutions have $2.05B invested in Agios Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 87 increasing their positions, 76 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
213
Holders Change
-5
Holders Change %
-2.29%
% of All Funds
2.86%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
22
Increased
87
Reduced
76
Closed
25
Calls
$11.2M
Puts
$8.65M
Net Calls
+$2.57M
Net Calls Change
+$3.05M

Top Buyers

1
PBA
Paradigm Biocapital Advisors
New York
+$38M
2
TCM
TCG Crossover Management
California
+$23.2M
3
RSCM
Rock Springs Capital Management
Maryland
+$21.5M
4
Wellington Management Group
Wellington Management Group
Massachusetts
+$13.2M
5
CP
Caligan Partners
New York
+$12.3M

Top Sellers

1
PCH
Polar Capital Holdings
United Kingdom
-$29.4M
2
AC
Armistice Capital
New York
-$29.3M
3
State Street
State Street
Massachusetts
-$16.6M
4
BlackRock
BlackRock
New York
-$9.15M
5
ACH
ArrowMark Colorado Holdings
Colorado
-$5.62M
Name Holding Trade Value Shares
Change 		Shares
Change %
AIP
151
Ameritas Investment Partners
Nebraska
$197K – – –
Carson Wealth (CWM LLC)
152
Carson Wealth (CWM LLC)
Nebraska
$176K +$121K +3,627 +219%
PNC Financial Services Group
153
PNC Financial Services Group
Pennsylvania
$147K +$27.8K +837 +23%
Mirae Asset Global Investments
154
Mirae Asset Global Investments
South Korea
$74.4K +$10.6K +320 +17%
BC
155
BIT Capital
Germany
$74.2K -$640K -19,238 -90%
AB
156
Amalgamated Bank
New York
$65K – – –
WSFS
157
Wilmington Savings Fund Society
Delaware
$62.7K -$7.52K -226 -11%
KBC Group
158
KBC Group
Belgium
$58K -$28.6K -864 -33%
SCM
159
Sterling Capital Management
North Carolina
$50.4K +$18K +540 +55%
GFM
160
GF Fund Management
China
$48.6K – – –
NA
161
NewEdge Advisors
Louisiana
$42.3K -$2.73K -82 -6%
BIG
162
Brooklyn Investment Group
New York
$37.6K +$37.6K +1,130 New
SO
163
STRS Ohio
Ohio
$36.6K -$236K -7,100 -87%
AssetMark Inc
164
AssetMark Inc
California
$31.8K +$4.99K +150 +19%
Nisa Investment Advisors
165
Nisa Investment Advisors
Missouri
$25.9K -$1.4K -42 -5%
A
166
AlphaQuest
New York
$22.3K +$9.85K +296 +79%
Federated Hermes
167
Federated Hermes
Pennsylvania
$19.9K -$508K -15,288 -96%
US Bancorp
168
US Bancorp
Minnesota
$18.9K +$333 +10 +2%
FHA
169
First Horizon Advisors
Tennessee
$17.4K -$698 -21 -4%
S
170
SignatureFD
Georgia
$17.1K +$1.2K +36 +8%
Lazard Asset Management
171
Lazard Asset Management
New York
$17K -$67.6K -2,124 -80%
Raymond James Financial
172
Raymond James Financial
Florida
$14.7K +$14.7K +442 New
HC
173
Hurley Capital
New York
$12.2K – – –
AP
174
Aspect Partners
Virginia
$12K – – –
Comerica Bank
175
Comerica Bank
Texas
$11.7K +$5.42K +163 +86%
5 6
7
8 9