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Agios Pharmaceuticals

236 hedge funds and large institutions have $1.67B invested in Agios Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 65 funds opening new positions, 79 increasing their positions, 69 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more funds holding

Funds holding:

3.91% less ownership

Funds ownership: 109.28%105.37% (-3.9%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

35% less capital invested

Capital invested by funds: $2.55B → $1.67B (-$878M)

Holders
236
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$133M
Puts
$45.6M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
126
Janus Henderson Group
United Kingdom
$648K
Zurich Cantonal Bank
127
Zurich Cantonal Bank
Switzerland
$643K
Rockefeller Capital Management
128
Rockefeller Capital Management
New York
$574K
ORI
129
Oak Ridge Investments
Illinois
$545K
BHCM
130
Brevan Howard Capital Management
Jersey
$526K
Handelsbanken Fonder
131
Handelsbanken Fonder
Sweden
$526K
ET
132
Entropy Technologies
New York
$522K
VC
133
VarCov Co
Connecticut
$520K
Canada Pension Plan Investment Board
134
Canada Pension Plan Investment Board
Ontario, Canada
$495K
DMKJ
135
David M. Knott Jr
$490K
II
136
Inspire Investing
Idaho
$466K
WG
137
Winton Group
United Kingdom
$456K
State Board of Administration of Florida Retirement System
138
State Board of Administration of Florida Retirement System
Florida
$431K
PFSRSONJ
139
Police & Firemen's Retirement System of New Jersey
New Jersey
$426K
ASRS
140
Arizona State Retirement System
Arizona
$417K
SEI Investments
141
SEI Investments
Pennsylvania
$391K
TI
142
Tidal Investments
Wisconsin
$388K
AI
143
Atria Investments
North Carolina
$383K
AA
144
AlphaCentric Advisors
Puerto Rico
$358K
Royal Bank of Canada
145
Royal Bank of Canada
Ontario, Canada
$354K
ProShare Advisors
146
ProShare Advisors
Maryland
$351K
Envestnet Asset Management
147
Envestnet Asset Management
Illinois
$347K
CB
148
Commerce Bank
Missouri
$344K
BC
149
Bridgefront Capital
Texas
$344K
FRM
150
Fox Run Management
Connecticut
$342K