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Agios Pharmaceuticals
AGIO

Overview Fund Activity

213 hedge funds and large institutions have $2.05B invested in Agios Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 87 increasing their positions, 76 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
213
Holders Change
-5
Holders Change %
-2.29%
% of All Funds
2.86%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
22
Increased
87
Reduced
76
Closed
25
Calls
$11.2M
Puts
$8.65M
Net Calls
+$2.57M
Net Calls Change
+$3.05M

Top Buyers

1
PBA
Paradigm Biocapital Advisors
New York
$38M
2
TCM
TCG Crossover Management
California
$23.2M
3
RSCM
Rock Springs Capital Management
Maryland
$32.9M
4
Wellington Management Group
Wellington Management Group
Massachusetts
$14M
5
CP
Caligan Partners
New York
$35.6M

Top Sellers

1
PCH
Polar Capital Holdings
United Kingdom
$0
2
AC
Armistice Capital
New York
$38.8M
3
State Street
State Street
Massachusetts
$64.9M
4
BlackRock
BlackRock
New York
$161M
5
ACH
ArrowMark Colorado Holdings
Colorado
$21.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
ProShare Advisors
126
ProShare Advisors
Maryland
$457K -$35.8K -1,077 -7%
AI
127
Atria Investments
North Carolina
$448K -$37.3K -1,122 -8%
PFSRSONJ
128
Police & Firemen's Retirement System of New Jersey
New Jersey
$430K +$29.6K +891 +7%
VIA
129
Virtus Investment Advisers
Connecticut
$428K +$116K +3,473 +37%
Creative Planning
130
Creative Planning
Kansas
$427K +$30.5K +917 +8%
HT
131
Headlands Technologies
Illinois
$421K +$64.2K +1,929 +18%
BNP Paribas Financial Markets
132
BNP Paribas Financial Markets
France
$396K +$252K +7,572 +175%
KK
133
KLP Kapitalforvaltning
Norway
$392K +$59.9K +1,800 +18%
II
134
Inspire Investing
Idaho
$390K -$1.33K -40 -0.3%
CUAMC
135
China Universal Asset Management Company
China
$387K +$4.62K +139 +1%
GFA
136
Gallagher Fiduciary Advisors
Illinois
$382K -$45.1K -1,357 -11%
PA
137
Profund Advisors
Maryland
$361K -$290K -8,731 -45%
SEI Investments
138
SEI Investments
Pennsylvania
$343K -$114K -3,421 -25%
Envestnet Asset Management
139
Envestnet Asset Management
Illinois
$336K -$414K -12,453 -55%
CB
140
Commerce Bank
Missouri
$319K +$46.7K +1,405 +17%
Russell Investments Group
141
Russell Investments Group
United Kingdom
$309K +$24.4K +734 +9%
TSS
142
Two Sigma Securities
New York
$288K +$288K +8,646 New
IC
143
IEQ Capital
California
$269K +$269K +8,086 New
JG
144
Jain Global
New York
$258K +$258K +7,749 New
CWM
145
CIBC World Markets
New York
$231K -$186K -5,582 -45%
SC
146
Savant Capital
Illinois
$229K +$229K +6,883 New
Public Employees Retirement Association of Colorado
147
Public Employees Retirement Association of Colorado
Colorado
$226K – – –
Cerity Partners
148
Cerity Partners
New York
$226K +$226K +6,789 New
Norges Bank
149
Norges Bank
Norway
$225K +$225K +6,756 New
TRCT
150
Tower Research Capital (TRC)
New York
$214K +$185K +5,563 +634%
4 5
6
7 8