AGIO icon

Agios Pharmaceuticals
AGIO

Overview Fund Activity

213 hedge funds and large institutions have $2.05B invested in Agios Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 87 increasing their positions, 76 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
213
Holders Change
-5
Holders Change %
-2.29%
% of All Funds
2.86%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
22
Increased
87
Reduced
76
Closed
25
Calls
$11.2M
Puts
$8.65M
Net Calls
+$2.57M
Net Calls Change
+$3.05M

Top Buyers

1
PBA
Paradigm Biocapital Advisors
New York
$38M
2
TCM
TCG Crossover Management
California
$23.2M
3
RSCM
Rock Springs Capital Management
Maryland
$32.9M
4
Wellington Management Group
Wellington Management Group
Massachusetts
$14M
5
CP
Caligan Partners
New York
$35.6M

Top Sellers

1
PCH
Polar Capital Holdings
United Kingdom
$0
2
AC
Armistice Capital
New York
$38.8M
3
State Street
State Street
Massachusetts
$64.9M
4
BlackRock
BlackRock
New York
$161M
5
ACH
ArrowMark Colorado Holdings
Colorado
$21.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
AA
101
ALPS Advisors
Colorado
$1.04M -$364K -10,945 -26%
Victory Capital Management
102
Victory Capital Management
Texas
$978K +$686K +20,630 +235%
BHCM
103
Brevan Howard Capital Management
Jersey
$970K +$970K +29,177 New
Ensign Peak Advisors
104
Ensign Peak Advisors
Utah
$831K -$231K -6,950 -22%
Janus Henderson Group
105
Janus Henderson Group
United Kingdom
$791K – – –
Royal Bank of Canada
106
Royal Bank of Canada
Ontario, Canada
$770K -$335K -10,073 -30%
IIM
107
INTECH Investment Management
Florida
$758K -$416K -12,496 -35%
SAI
108
Savvy Advisors Inc
New York
$724K +$724K +21,781 New
Canada Life
109
Canada Life
Manitoba, Canada
$654K +$8.48K +255 +1%
Handelsbanken Fonder
110
Handelsbanken Fonder
Sweden
$643K – – –
Fidelity Investments
111
Fidelity Investments
Massachusetts
$618K +$26.1K +786 +4%
GC
112
Guggenheim Capital
Illinois
$595K -$28.3K -851 -5%
FRM
113
Fox Run Management
Connecticut
$589K +$589K +17,707 New
Thrivent Financial for Lutherans
114
Thrivent Financial for Lutherans
Minnesota
$583K – – –
CM
115
Caption Management
Oklahoma
$565K -$1.76M -53,000 -76%
ASRS
116
Arizona State Retirement System
Arizona
$555K +$65.8K +1,978 +13%
EGM
117
Engineers Gate Manager
New York
$550K -$205K -6,169 -27%
Zurich Cantonal Bank
118
Zurich Cantonal Bank
Switzerland
$545K +$118K +3,560 +28%
State Board of Administration of Florida Retirement System
119
State Board of Administration of Florida Retirement System
Florida
$527K – – –
TI
120
Tidal Investments
Wisconsin
$518K -$122K -3,658 -19%
VOYA Investment Management
121
VOYA Investment Management
Georgia
$512K +$5.36K +161 +1%
Teacher Retirement System of Texas
122
Teacher Retirement System of Texas
Texas
$512K +$53K +1,592 +12%
CC
123
Centiva Capital
New York
$500K +$266 +8 +0.1%
HWAM
124
Hennion & Walsh Asset Management
New Jersey
$499K +$499K +15,005 New
PAMP
125
Polar Asset Management Partners
Ontario, Canada
$489K +$489K +14,700 New
3 4
5
6 7