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Agios Pharmaceuticals

237 hedge funds and large institutions have $1.67B invested in Agios Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 65 funds opening new positions, 79 increasing their positions, 70 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $133M | Put options by funds: $45.6M

48% more first-time investments, than exits

New positions opened: 65 | Existing positions closed: 44

13% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 70

8% more funds holding

Funds holding: 220237 (+17)

4.24% less ownership

Funds ownership: 109.29%105.05% (-4.2%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

35% less capital invested

Capital invested by funds: $2.55B → $1.67B (-$879M)

Holders
237
Holders Change
+17
Holders Change %
+7.73%
% of All Funds
2.88%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
65
Increased
79
Reduced
70
Closed
44
Calls
$133M
Puts
$45.6M
Net Calls
+$87.2M
Net Calls Change
+$80.1M
Name Holding Trade Value Shares
Change
Change in
Stake
PAM
76
Panagora Asset Management
Massachusetts
$2.17M +$2.8M +79,840 New
YIH
77
Y-Intercept (HK)
Hong Kong
$2.17M +$2.52M +71,899 +906%
LCM
78
Lynx1 Capital Management
Puerto Rico
$2.17M +$2.79M +79,624 New
First Trust Advisors
79
First Trust Advisors
Illinois
$2.14M +$148K +4,227 +6%
WP
80
Woodline Partners
California
$2.03M +$15K +427 +0.6%
RhumbLine Advisers
81
RhumbLine Advisers
Massachusetts
$2.02M -$475K -13,549 -15%
ECM
82
ExodusPoint Capital Management
New York
$1.94M +$2.5M +71,146 New
Manulife (Manufacturers Life Insurance)
83
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.92M -$904K -25,756 -27%
KCM
84
Kennedy Capital Management
Missouri
$1.79M +$1.44M +41,014 +166%
Wells Fargo
85
Wells Fargo
California
$1.76M +$702K +20,018 +45%
AllianceBernstein
86
AllianceBernstein
Tennessee
$1.67M -$316 -9 -0%
Tudor Investment Corp
87
Tudor Investment Corp
Connecticut
$1.67M +$2.15M +61,345 New
Universal-Beteiligungs- und Servicegesellschaft
88
Universal-Beteiligungs- und Servicegesellschaft
Germany
$1.65M -$374K -10,653 -15%
TD Asset Management
89
TD Asset Management
Ontario, Canada
$1.56M -$2.49M -71,002 -55%
California State Teachers Retirement System (CalSTRS)
90
California State Teachers Retirement System (CalSTRS)
California
$1.45M -$283K -8,057 -13%
HT
91
Headlands Technologies
Illinois
$1.44M +$1.85M +52,739 New
New York State Common Retirement Fund
92
New York State Common Retirement Fund
New York
$1.41M +$67.3K +1,917 +4%
EGM
93
Engineers Gate Manager
New York
$1.34M +$1.72M +49,128 New
AA
94
ALPS Advisors
Colorado
$1.3M +$713K +20,327 +74%
State of New Jersey Common Pension Fund D
95
State of New Jersey Common Pension Fund D
New Jersey
$1.29M +$1.66M +47,414 New
DekaBank Deutsche Girozentrale
96
DekaBank Deutsche Girozentrale
Germany
$1.27M
SG Americas Securities
97
SG Americas Securities
New York
$1.26M +$660K +18,801 +68%
Schroder Investment Management Group
98
Schroder Investment Management Group
United Kingdom
$1.26M +$1.62M +46,242 New
XT
99
XTX Topco
Cayman Islands
$1.25M +$1.62M +46,039 New
VRS
100
Virginia Retirement Systems
Virginia
$1.13M +$10.5K +300 +0.7%