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Agios Pharmaceuticals
AGIO

Overview Fund Activity

213 hedge funds and large institutions have $2.05B invested in Agios Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 87 increasing their positions, 76 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
213
Holders Change
-5
Holders Change %
-2.29%
% of All Funds
2.86%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
22
Increased
87
Reduced
76
Closed
25
Calls
$11.2M
Puts
$8.65M
Net Calls
+$2.57M
Net Calls Change
+$3.05M

Top Buyers

1
PBA
Paradigm Biocapital Advisors
New York
$38M
2
TCM
TCG Crossover Management
California
$23.2M
3
RSCM
Rock Springs Capital Management
Maryland
$32.9M
4
Wellington Management Group
Wellington Management Group
Massachusetts
$14M
5
CP
Caligan Partners
New York
$35.6M

Top Sellers

1
PCH
Polar Capital Holdings
United Kingdom
$0
2
AC
Armistice Capital
New York
$38.8M
3
State Street
State Street
Massachusetts
$64.9M
4
BlackRock
BlackRock
New York
$161M
5
ACH
ArrowMark Colorado Holdings
Colorado
$21.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
Barclays
51
Barclays
United Kingdom
$6.01M +$2.25M +67,551 +60%
TD Asset Management
52
TD Asset Management
Ontario, Canada
$5.59M -$329K -9,878 -6%
Prudential Financial
53
Prudential Financial
New Jersey
$5.27M -$1.53M -45,883 -22%
PSC
54
Patient Square Capital
California
$4.65M – – –
Allianz Asset Management
55
Allianz Asset Management
Germany
$4.62M +$1.55M +46,665 +51%
CF
56
Cantor Fitzgerald
New York
$4.46M +$3.4M +102,200 +319%
Manulife (Manufacturers Life Insurance)
57
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$4.39M +$17K +512 +0.4%
Hudson Bay Capital Management
58
Hudson Bay Capital Management
Connecticut
$4.32M +$641K +19,280 +17%
American Century Companies
59
American Century Companies
Missouri
$4.25M +$422K +12,700 +11%
NL
60
Nuveen LLC
North Carolina
$3.98M +$1.2M +36,171 +43%
UBS Group
61
UBS Group
Switzerland
$3.95M -$426K -12,808 -10%
Invesco
62
Invesco
Georgia
$3.75M +$175K +5,250 +5%
Swiss National Bank
63
Swiss National Bank
Switzerland
$3.64M +$333K +10,000 +10%
CC
64
Casdin Capital
New York
$3.33M -$4.99M -150,000 -60%
TI
65
Trexquant Investment
Connecticut
$3.27M +$3.27M +98,401 New
AQR Capital Management
66
AQR Capital Management
Connecticut
$3.21M +$1.51M +45,407 +88%
RhumbLine Advisers
67
RhumbLine Advisers
Massachusetts
$2.99M +$101K +3,039 +3%
AG
68
Algert Global
California
$2.95M +$466K +14,020 +19%
SAM
69
Silvercrest Asset Management
New York
$2.75M – – –
MCM
70
Moore Capital Management
New York
$2.66M +$665K +20,000 +33%
HS
71
HighVista Strategies
Massachusetts
$2.33M +$865K +26,022 +59%
Capital Fund Management (CFM)
72
Capital Fund Management (CFM)
France
$2.28M -$126K -3,800 -5%
Susquehanna International Group
73
Susquehanna International Group
Pennsylvania
$2.27M -$461K -13,859 -17%
Qube Research & Technologies (QRT)
74
Qube Research & Technologies (QRT)
United Kingdom
$2.24M -$2.02M -60,601 -47%
Legal & General Group
75
Legal & General Group
United Kingdom
$2.14M +$142K +4,262 +7%
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