We are live on ! Find out more
AGIO icon

Agios Pharmaceuticals

232 hedge funds and large institutions have $2.12B invested in Agios Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 82 increasing their positions, 81 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed

620% more call options, than puts

Call options by funds: $127M | Put options by funds: $17.6M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

27% more capital invested

Capital invested by funds: $1.67B → $2.12B (+$452M)

2.54% more ownership

Funds ownership: 105.05%107.59% (+2.5%)

1% more repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 81

0% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 36

2% less funds holding

Funds holding: 237232 (-5)

Holders
232
Holders Change
-5
Holders Change %
-2.11%
% of All Funds
2.86%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
36
Increased
82
Reduced
81
Closed
36
Calls
$127M
Puts
$17.6M
Net Calls
+$109M
Net Calls Change
+$22M
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
26
SCS Capital Management
Massachusetts
$20.7M +$399K +14,085 +2%
FCMV
27
Foresite Capital Management VI
California
$17.8M -$142K -5,000 -0.9%
Northern Trust
28
Northern Trust
Illinois
$17.2M -$74.5K -2,629 -0.5%
Bank of America
29
Bank of America
North Carolina
$17.2M -$891K -31,441 -6%
Artisan Partners
30
Artisan Partners
Wisconsin
$16.3M -$651K -22,969 -5%
Charles Schwab
31
Charles Schwab
California
$16.1M -$158K -5,590 -1%
Connor, Clark & Lunn Investment Management (CC&L)
32
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$15.2M -$3.19M -112,549 -20%
VPC
33
Vestal Point Capital
New York
$15.2M +$3.54M +125,000 +38%
Marshall Wace
34
Marshall Wace
United Kingdom
$15.2M +$2.68M +94,479 +27%
Legal & General Group
35
Legal & General Group
United Kingdom
$14.3M +$2.71M +95,704 +29%
ACH
36
ArrowMark Colorado Holdings
Colorado
$13.7M -$1.77M -62,561 -13%
PHP
37
Parkman Healthcare Partners
Connecticut
$13.7M +$8.62M +303,921 +305%
VFT
38
Vanguard Fiduciary Trust
Pennsylvania
$12.9M +$10.8M +382,021 New
BNP Paribas Financial Markets
39
BNP Paribas Financial Markets
France
$11.1M +$2.4M +84,787 +35%
T. Rowe Price Associates
40
T. Rowe Price Associates
Maryland
$10.1M -$9.61M -339,103 -53%
KCM
41
Kennedy Capital Management
Missouri
$9.32M +$5.95M +209,801 +320%
AG
42
Algert Global
California
$9.08M -$4.13M -145,783 -35%
Two Sigma Investments
43
Two Sigma Investments
New York
$8.51M -$1.38M -48,520 -16%
Arrowstreet Capital
44
Arrowstreet Capital
Massachusetts
$8.47M +$7.1M +250,461 New
PAM
45
Panagora Asset Management
Massachusetts
$8.07M +$4.5M +158,628 +199%
PAI
46
Palo Alto Investors
California
$7.23M +$31.2K +1,102 +0.5%
SFCM
47
Seven Fleet Capital Management
California
$7.09M +$5.04M +177,809 +560%
Squarepoint
48
Squarepoint
New York
$7.07M +$2.47M +87,125 +72%
SSA
49
Schonfeld Strategic Advisors
New York
$6.77M +$5.67M +200,061 New
EP
50
Eversept Partners
New York
$6.77M +$5.67M +200,000 New

AGIO Hedge Fund Activity: Q1 2026 in Review

232 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Agios Pharmaceuticals (AGIO) for Q1 2026, worth a combined $2.12B — up 27% from $1.67B a quarter earlier.

Fund positioning in AGIO was balanced in Q1 2026: 36 funds opened new positions, 36 closed out, 82 added to existing stakes and 81 trimmed.

The largest buyer was Lynx1 Capital Management, adding an estimated $71.8M. The largest seller was TCG Crossover Management, exiting entirely with an estimated $32.2M sold.

  • 232 institutional investors held Agios Pharmaceuticals (AGIO) as of Q1 2026, down from 237 in Q4 2025.
  • Funds reported $2.12B of Agios Pharmaceuticals stock for Q1 2026, up 27% quarter-over-quarter.
  • 36 funds opened new Agios Pharmaceuticals positions in Q1 2026 and 36 closed out, a net change of 0 holders.
  • The largest Agios Pharmaceuticals buyer in Q1 2026 was Lynx1 Capital Management, an estimated $71.8M added.
  • The largest Agios Pharmaceuticals seller in Q1 2026 was TCG Crossover Management, an estimated $32.2M sold.

Based on aggregated 13F filings for Q1 2026.