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Agios Pharmaceuticals

237 hedge funds and large institutions have $1.67B invested in Agios Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 65 funds opening new positions, 79 increasing their positions, 70 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $133M | Put options by funds: $45.6M

48% more first-time investments, than exits

New positions opened: 65 | Existing positions closed: 44

13% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 70

8% more funds holding

Funds holding: 220237 (+17)

4.24% less ownership

Funds ownership: 109.29%105.05% (-4.2%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

35% less capital invested

Capital invested by funds: $2.55B → $1.67B (-$879M)

Holders
237
Holders Change
+17
Holders Change %
+7.73%
% of All Funds
2.88%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
65
Increased
79
Reduced
70
Closed
44
Calls
$133M
Puts
$45.6M
Net Calls
+$87.2M
Net Calls Change
+$80.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Wellington Management Group
26
Wellington Management Group
Massachusetts
$16.3M -$65.7M -1,873,590 -76%
Connor, Clark & Lunn Investment Management (CC&L)
27
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$15.3M +$1.14M +32,544 +6%
Bank of America
28
Bank of America
North Carolina
$14.7M -$20.7M -590,659 -52%
FCMV
29
Foresite Capital Management VI
California
$14.4M +$18.6M +530,000 New
Northern Trust
30
Northern Trust
Illinois
$13.9M -$1.53M -43,509 -8%
Artisan Partners
31
Artisan Partners
Wisconsin
$13.7M +$3.56M +101,542 +25%
Charles Schwab
32
Charles Schwab
California
$13.1M +$15.3K +436 +0.1%
ACH
33
ArrowMark Colorado Holdings
Colorado
$12.7M -$7.5M -213,771 -31%
AG
34
Algert Global
California
$11.3M +$13.3M +378,448 +1,058%
Millennium Management
35
Millennium Management
New York
$10.8M +$13.8M +393,218 +7,788%
Qube Research & Technologies (QRT)
36
Qube Research & Technologies (QRT)
United Kingdom
$10.3M +$13.3M +378,373 New
Marshall Wace
37
Marshall Wace
United Kingdom
$9.63M +$4.45M +126,815 +56%
Legal & General Group
38
Legal & General Group
United Kingdom
$8.93M +$185K +5,277 +2%
VPC
39
Vestal Point Capital
New York
$8.85M +$6.95M +198,000 +156%
Barclays
40
Barclays
United Kingdom
$8.72M +$3.66M +104,312 +48%
Two Sigma Investments
41
Two Sigma Investments
New York
$8.17M +$8.44M +240,527 +403%
N
42
Nuveen
North Carolina
$8.11M +$6.26M +178,328 +149%
JP Morgan Chase
43
JP Morgan Chase
New York
$6.85M +$2.41M +68,677 +38%
BNP Paribas Financial Markets
44
BNP Paribas Financial Markets
France
$6.61M +$8M +227,972 +1,551%
TI
45
Trexquant Investment
Connecticut
$6.17M +$7.95M +226,600 New
PAI
46
Palo Alto Investors
California
$5.78M -$1.86M -52,998 -20%
Pictet Asset Management
47
Pictet Asset Management
Switzerland
$5.57M -$2.36M -67,142 -25%
Point72 Asset Management
48
Point72 Asset Management
Connecticut
$5.44M +$6.79M +193,493 +2,974%
Bank of New York Mellon
49
Bank of New York Mellon
New York
$5.36M -$2.57M -73,203 -27%
ACM
50
ADAR1 Capital Management
Texas
$5.12M +$5.3M +151,000 +408%