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Agios Pharmaceuticals
AGIO

Overview Fund Activity

218 hedge funds and large institutions have $1.76B invested in Agios Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 38 funds opening new positions, 73 increasing their positions, 77 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
218
Holders Change
-5
Holders Change %
-2.24%
% of All Funds
2.96%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
38
Increased
73
Reduced
77
Closed
40
Calls
$10.6M
Puts
$11.1M
Net Calls
-$481K
Net Calls Change
+$2M

Top Buyers

1
CC
1
Commodore Capital
New York
$64M
2
Bank of America
2
Bank of America
North Carolina
$33.3M
3
SCM
3
SCS Capital Management
Massachusetts
$17.9M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$21.8M
5
PCH
5
Polar Capital Holdings
United Kingdom
$29.4M

Top Sellers

1
JFG
1
Jefferies Financial Group
New York
$0
2
BI
2
BVF Inc
California
$0
3
Citadel Advisors
3
Citadel Advisors
Florida
$25.3M
4
Loomis, Sayles & Company
4
Loomis, Sayles & Company
Massachusetts
$0
5
PBA
5
Paradigm Biocapital Advisors
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
SCM
26
SCS Capital Management
Massachusetts
$17.9M +$17.9M +611,098 New
Northern Trust
27
Northern Trust
Illinois
$16.9M -$563K -19,222 -3%
D.E. Shaw & Co
28
D.E. Shaw & Co
New York
$16.3M +$1.12M +38,345 +7%
Marshall Wace
29
Marshall Wace
United Kingdom
$15.3M -$3.25M -110,755 -18%
Charles Schwab
30
Charles Schwab
California
$13.6M -$222K -7,589 -2%
Artisan Partners
31
Artisan Partners
Wisconsin
$12M -$2.59M -88,462 -18%
Connor, Clark & Lunn Investment Management (CC&L)
32
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$11.3M +$7.64M +260,845 +208%
RSCM
33
Rock Springs Capital Management
Maryland
$10M -$3.78M -128,906 -27%
Voloridge Investment Management
34
Voloridge Investment Management
Florida
$9.72M +$3.84M +131,162 +65%
EHI
35
Eagle Health Investments
Connecticut
$9.69M – – –
O
36
OrbiMed
New York
$9.54M +$8.75M +298,800 +1,119%
Pictet Asset Management
37
Pictet Asset Management
Switzerland
$9.4M -$1.32M -43,674 -12%
Morgan Stanley
38
Morgan Stanley
New York
$8.63M -$2.45M -83,466 -22%
PAI
39
Palo Alto Investors
California
$8.1M +$8.1M +276,578 New
Bank of New York Mellon
40
Bank of New York Mellon
New York
$7.72M -$60.5K -2,064 -0.8%
BFM
41
Boothbay Fund Management
New York
$7.65M +$277K +9,447 +4%
CC
42
Casdin Capital
New York
$7.33M – – –
CCM
43
Cutter Capital Management
New York
$6.9M -$1.94M -66,273 -22%
Axa
44
Axa
France
$6.6M +$1.46M +49,742 +28%
Nordea Investment Management
45
Nordea Investment Management
Sweden
$6.51M +$105K +3,604 +2%
Prudential Financial
46
Prudential Financial
New Jersey
$5.98M +$2.91M +99,320 +95%
TD Asset Management
47
TD Asset Management
Ontario, Canada
$5.22M +$363K +12,400 +7%
Citigroup
48
Citigroup
New York
$5.16M -$499K -17,024 -9%
NL
49
Nuveen LLC
North Carolina
$4.43M +$4.43M +83,409 New
Walleye Capital
50
Walleye Capital
New York
$4.41M -$1.44M -49,027 -25%
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