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Agios Pharmaceuticals
AGIO

160 hedge funds and large institutions have $1.95B invested in Agios Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 28 funds opening new positions, 47 increasing their positions, 61 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

5.71% more ownership

Funds ownership: 103.31% → 109.02% (+5.7%)

2% less funds holding

Funds holding: 164 → 160 (-4)

13% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 32

23% less repeat investments, than reductions

Existing positions increased: 47 | Existing positions reduced: 61

31% less capital invested

Capital invested by funds: $2.81B → $1.95B (-$865M)

51% less call options, than puts

Call options by funds: $6.91M | Put options by funds: $14M

100% less funds holding in top 10

Funds holding in top 10: 2 → 0 (-2)

Holders
160
Holders Change
-4
Holders Change %
-2.44%
% of All Funds
2.46%
Holding in Top 10
–
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-100%
% of All Funds
–
New
28
Increased
47
Reduced
61
Closed
32
Calls
$6.91M
Puts
$14M
Net Calls
-$7.06M
Net Calls Change
-$3.42M

Top Buyers

1
State Street
State Street
Massachusetts
+$24.2M
2
FCM
Farallon Capital Management
California
+$17.6M
3
EAM
Erste Asset Management
Austria
+$17.5M
4
ACH
ArrowMark Colorado Holdings
Colorado
+$9.33M
5
EHI
Eagle Health Investments
Connecticut
+$7.89M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$56.9M
2
JP Morgan Chase
JP Morgan Chase
New York
-$46M
3
ClearBridge Investments
ClearBridge Investments
New York
-$42.7M
4
Vanguard Group
Vanguard Group
Pennsylvania
-$15.2M
5
BlackRock
BlackRock
New York
-$14M
Name Holding Trade Value Shares
Change 		Change in
Stake
Bank of New York Mellon
26
Bank of New York Mellon
New York
$12.1M +$3.61M +89,698 +32%
Jacobs Levy Equity Management
27
Jacobs Levy Equity Management
New Jersey
$10.1M +$221K +5,494 +2%
Bank of America
28
Bank of America
North Carolina
$9.28M +$5.87M +145,719 +107%
Morgan Stanley
29
Morgan Stanley
New York
$8.48M +$3.29M +81,643 +46%
Norges Bank
30
Norges Bank
Norway
$6.76M -$3.62M -89,911 -30%
Hudson Bay Capital Management
31
Hudson Bay Capital Management
Connecticut
$6.57M +$5.03M +125,000 +167%
UBS Group
32
UBS Group
Switzerland
$6.09M +$3.68M +91,504 +97%
Rafferty Asset Management
33
Rafferty Asset Management
New York
$5.86M +$4.4M +109,293 +158%
Citigroup
34
Citigroup
New York
$5.03M +$3.95M +98,113 +179%
Swiss National Bank
35
Swiss National Bank
Switzerland
$3.84M -$229K -5,700 -5%
D.E. Shaw & Co
36
D.E. Shaw & Co
New York
$3.74M -$1.08M -26,888 -19%
PAMS
37
Pictet Asset Management (Switzerland)
Switzerland
$3.61M +$196K +4,878 +5%
Principal Financial Group
38
Principal Financial Group
Iowa
$3.31M -$445K -11,054 -10%
Millennium Management
39
Millennium Management
New York
$2.97M +$3.09M +76,651 +564%
TD Asset Management
40
TD Asset Management
Ontario, Canada
$2.85M +$758K +18,820 +28%
Connor, Clark & Lunn Investment Management (CC&L)
41
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.81M -$750K -18,645 -18%
Tudor Investment Corp
42
Tudor Investment Corp
Connecticut
$2.75M +$3.37M +83,815 New
CS
43
Credit Suisse
Switzerland
$2.75M -$24K -596 -0.7%
Susquehanna International Group
44
Susquehanna International Group
Pennsylvania
$2.7M -$4.47M -110,974 -57%
RhumbLine Advisers
45
RhumbLine Advisers
Massachusetts
$2.69M -$171K -4,239 -5%
State of Wisconsin Investment Board
46
State of Wisconsin Investment Board
Wisconsin
$2.63M – – –
EVM
47
Eaton Vance Management
Massachusetts
$2.46M – – –
California State Teachers Retirement System (CalSTRS)
48
California State Teachers Retirement System (CalSTRS)
California
$2.45M -$113K -2,817 -4%
State of New Jersey Common Pension Fund D
49
State of New Jersey Common Pension Fund D
New Jersey
$2.42M +$430K +10,680 +17%
AllianceBernstein
50
AllianceBernstein
Tennessee
$2.41M – – –
1
2
3 4 5

AGIO Hedge Fund Activity: Q4 2021 in Review

160 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Agios Pharmaceuticals (AGIO) for Q4 2021, worth a combined $1.95B — down 31% from $2.81B a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of AGIO and 28 opened new positions — a net loss of 4 holders — while 61 trimmed existing stakes and 47 added.

The largest buyer was State Street, adding an estimated $24.2M. The largest seller was Fidelity Investments, cutting an estimated $56.9M.

  • 160 institutional investors held Agios Pharmaceuticals (AGIO) as of Q4 2021, down from 164 in Q3 2021.
  • Funds reported $1.95B of Agios Pharmaceuticals stock for Q4 2021, down 31% quarter-over-quarter.
  • 28 funds opened new Agios Pharmaceuticals positions in Q4 2021 and 32 closed out, a net change of -4 holders.
  • The largest Agios Pharmaceuticals buyer in Q4 2021 was State Street, an estimated $24.2M added.
  • The largest Agios Pharmaceuticals seller in Q4 2021 was Fidelity Investments, an estimated $56.9M sold.

Based on aggregated 13F filings for Q4 2021.