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Agios Pharmaceuticals

232 hedge funds and large institutions have $2.12B invested in Agios Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 36 funds opening new positions, 82 increasing their positions, 81 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed

620% more call options, than puts

Call options by funds: $127M | Put options by funds: $17.6M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

27% more capital invested

Capital invested by funds: $1.67B → $2.12B (+$452M)

2.54% more ownership

Funds ownership: 105.05%107.59% (+2.5%)

1% more repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 81

0% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 36

2% less funds holding

Funds holding: 237232 (-5)

Holders
232
Holders Change
-5
Holders Change %
-2.11%
% of All Funds
2.86%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
36
Increased
82
Reduced
81
Closed
36
Calls
$127M
Puts
$17.6M
Net Calls
+$109M
Net Calls Change
+$22M
Name Holding Trade Value Shares
Change
Change in
Stake
WG
251
Winton Group
United Kingdom
-$456K -16,751 Closed
FRM
252
Fox Run Management
Connecticut
-$342K -12,567 Closed
A
253
AlphaQuest
New York
-$326K -11,963 Closed
Capstone Investment Advisors
254
Capstone Investment Advisors
New York
-$282K -10,355 Closed
SO
255
STRS Ohio
Ohio
-$272K -10,000 Closed
TSS
256
Two Sigma Securities
New York
-$250K -9,198 Closed
CCIA
257
Campbell & Co Investment Adviser
Maryland
-$224K -8,226 Closed
GAM
258
Griffin Asset Management
New York
-$201K -7,382 Closed
CIM
259
Contravisory Investment Management
Massachusetts
-$168K -6,189 Closed
QL
260
Quarry LP
New York
-$81.7K -3,000 Closed
AB
261
Amalgamated Bank
New York
-$48K -1,774 Closed
TM
262
Torren Management
California
-$16.7K -615 Closed
QT
263
Quantbot Technologies
New York
-$10.5K -386 Closed
AP
264
Aspect Partners
Virginia
-$9.83K -361 Closed
Daiwa Securities Group
265
Daiwa Securities Group
Japan
-$6K -204 Closed
CWP
266
Concord Wealth Partners
Virginia
-$5.44K -200 Closed
BBHC
267
Brown Brothers Harriman & Co
New York
-$3.92K -144 Closed
C
268
Covestor
United Kingdom
-$1.08K -38 -93%

AGIO Hedge Fund Activity: Q1 2026 in Review

232 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Agios Pharmaceuticals (AGIO) for Q1 2026, worth a combined $2.12B — up 27% from $1.67B a quarter earlier.

Fund positioning in AGIO was balanced in Q1 2026: 36 funds opened new positions, 36 closed out, 82 added to existing stakes and 81 trimmed.

The largest buyer was Lynx1 Capital Management, adding an estimated $71.8M. The largest seller was TCG Crossover Management, exiting entirely with an estimated $32.2M sold.

  • 232 institutional investors held Agios Pharmaceuticals (AGIO) as of Q1 2026, down from 237 in Q4 2025.
  • Funds reported $2.12B of Agios Pharmaceuticals stock for Q1 2026, up 27% quarter-over-quarter.
  • 36 funds opened new Agios Pharmaceuticals positions in Q1 2026 and 36 closed out, a net change of 0 holders.
  • The largest Agios Pharmaceuticals buyer in Q1 2026 was Lynx1 Capital Management, an estimated $71.8M added.
  • The largest Agios Pharmaceuticals seller in Q1 2026 was TCG Crossover Management, an estimated $32.2M sold.

Based on aggregated 13F filings for Q1 2026.