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AGEN

Agenus

96 hedge funds and large institutions have $31.8M invested in Agenus in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 24 increasing their positions, 30 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

630% more call options, than puts

Call options by funds: $745K | Put options by funds: $102K

120% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 10

10% more funds holding

Funds holding: 8796 (+9)

2.17% more ownership

Funds ownership: 27.6%29.77% (+2.2%)

6% less capital invested

Capital invested by funds: $33.9M → $31.8M (-$2.08M)

20% less repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 30

Holders
96
Holders Change
+9
Holders Change %
+10.34%
% of All Funds
1.17%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
22
Increased
24
Reduced
30
Closed
10
Calls
$745K
Puts
$102K
Net Calls
+$643K
Net Calls Change
-$862K
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$8.89M +$1.04M +261,203 +10%
SL
2
Siren LLC
Connecticut
$3.34M
Acadian Asset Management
3
Acadian Asset Management
Massachusetts
$1.95M +$1.66M +417,393 +204%
BlackRock
4
BlackRock
New York
$1.75M +$44.7K +11,233 +2%
Renaissance Technologies
5
Renaissance Technologies
New York
$1.71M +$1.9M +477,346 +721%
Citadel Advisors
6
Citadel Advisors
Florida
$1.33M +$1.69M +423,242 New
Geode Capital Management
7
Geode Capital Management
Massachusetts
$1.17M +$103K +25,757 +7%
Morgan Stanley
8
Morgan Stanley
New York
$896K -$1.05M -263,928 -48%
Susquehanna International Group
9
Susquehanna International Group
Pennsylvania
$734K +$170K +42,720 +22%
Millennium Management
10
Millennium Management
New York
$708K -$491K -123,415 -35%
JF
11
Jump Financial
Illinois
$535K +$115K +28,913 +20%
PAM
12
Panagora Asset Management
Massachusetts
$512K +$147K +36,964 +29%
Marshall Wace
13
Marshall Wace
United Kingdom
$461K +$133K +33,487 +30%
Raymond James Financial
14
Raymond James Financial
Florida
$445K -$16.4K -4,107 -3%
State Street
15
State Street
Massachusetts
$431K -$52.6K -13,200 -9%
D.E. Shaw & Co
16
D.E. Shaw & Co
New York
$401K +$53K +13,309 +12%
Walleye Capital
17
Walleye Capital
New York
$388K -$746K -187,330 -60%
UBS Group
18
UBS Group
Switzerland
$373K +$147K +36,881 +45%
Two Sigma Investments
19
Two Sigma Investments
New York
$368K +$58.8K +14,764 +14%
6CM
20
683 Capital Management
New York
$359K +$455K +114,336 New
Man Group
21
Man Group
United Kingdom
$359K +$455K +114,204 New
Point72 Asset Management
22
Point72 Asset Management
Connecticut
$340K +$431K +108,220 New
OAC
23
OMERS Administration Corp
Ontario, Canada
$316K +$400K +100,500 New
Northern Trust
24
Northern Trust
Illinois
$281K +$31.4K +7,888 +10%
Jane Street
25
Jane Street
New York
$231K +$82.8K +20,794 +39%

AGEN Hedge Fund Activity: Q4 2025 in Review

96 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Agenus (AGEN) for Q4 2025, worth a combined $31.8M — down 6.1% from $33.9M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new AGEN positions and 10 closed out — a net gain of 12 holders — while 24 added to existing stakes and 30 trimmed.

The largest buyer was Renaissance Technologies, adding an estimated $1.9M. The largest seller was Bank of America, cutting an estimated $1.42M.

  • 96 institutional investors held Agenus (AGEN) as of Q4 2025, up from 87 in Q3 2025.
  • Funds reported $31.8M of Agenus stock for Q4 2025, down 6.1% quarter-over-quarter.
  • 22 funds opened new Agenus positions in Q4 2025 and 10 closed out, a net change of +12 holders.
  • The largest Agenus buyer in Q4 2025 was Renaissance Technologies, an estimated $1.9M added.
  • The largest Agenus seller in Q4 2025 was Bank of America, an estimated $1.42M sold.

Based on aggregated 13F filings for Q4 2025.