Agenus
AGEN
96 hedge funds and large institutions have $31.8M invested in Agenus in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 24 increasing their positions, 30 reducing their positions, and 10 closing their positions.
630% more call options, than puts
Call options by funds: $745K | Put options by funds: $102K
120% more first-time investments, than exits
New positions opened: 22 | Existing positions closed: 10
10% more funds holding
Funds holding: 87 → 96 (+9)
2.17% more ownership
Funds ownership: 27.6% → 29.77% (+2.2%)
6% less capital invested
Capital invested by funds: $33.9M → $31.8M (-$2.08M)
20% less repeat investments, than reductions
Existing positions increased: 24 | Existing positions reduced: 30
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Renaissance Technologies
New York
|
+$1.9M |
| 2 |
Citadel Advisors
Miami,
Florida
|
+$1.69M |
| 3 |
Acadian Asset Management
Boston,
Massachusetts
|
+$1.66M |
| 4 |
Vanguard Group
Malvern,
Pennsylvania
|
+$1.04M |
| 5 |
6CM
683 Capital Management
New York
|
+$455K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Bank of America
Charlotte,
North Carolina
|
-$1.42M |
| 2 |
Morgan Stanley
New York
|
-$1.05M |
| 3 |
Walleye Capital
New York
|
-$746K |
| 4 |
TGIA
Torrey Growth & Income Advisors
Del Mar,
California
|
-$507K |
| 5 |
Millennium Management
New York
|
-$491K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
101
Comerica Bank
Dallas,
Texas
| – | -$4.07K | -1,058 | Closed |
|
102
Citigroup
New York
| – | -$2.11K | -547 | Closed |
|
103
PNC Financial Services Group
Pittsburgh,
Pennsylvania
| – | -$243 | -63 | Closed |
|
|
EP
104
Essential Partners
Rancho Santa Fe,
California
| – | -$35 | -9 | Closed |
|
|
ASN
105
Advisory Services Network
Atlanta,
Georgia
| – | -$19 | -5 | Closed |
|
|
FRA
106
Front Row Advisors
Tiburon,
California
| – | -$4 | -1 | Closed |
|
AGEN Hedge Fund Activity: Q4 2025 in Review
96 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Agenus (AGEN) for Q4 2025, worth a combined $31.8M — down 6.1% from $33.9M a quarter earlier.
Buyers outnumbered sellers: 22 funds opened new AGEN positions and 10 closed out — a net gain of 12 holders — while 24 added to existing stakes and 30 trimmed.
The largest buyer was Renaissance Technologies, adding an estimated $1.9M. The largest seller was Bank of America, cutting an estimated $1.42M.
- 96 institutional investors held Agenus (AGEN) as of Q4 2025, up from 87 in Q3 2025.
- Funds reported $31.8M of Agenus stock for Q4 2025, down 6.1% quarter-over-quarter.
- 22 funds opened new Agenus positions in Q4 2025 and 10 closed out, a net change of +12 holders.
- The largest Agenus buyer in Q4 2025 was Renaissance Technologies, an estimated $1.9M added.
- The largest Agenus seller in Q4 2025 was Bank of America, an estimated $1.42M sold.
Based on aggregated 13F filings for Q4 2025.