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AGEN

Agenus

96 hedge funds and large institutions have $31.8M invested in Agenus in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 24 increasing their positions, 30 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

630% more call options, than puts

Call options by funds: $745K | Put options by funds: $102K

120% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 10

10% more funds holding

Funds holding: 8796 (+9)

2.17% more ownership

Funds ownership: 27.6%29.77% (+2.2%)

6% less capital invested

Capital invested by funds: $33.9M → $31.8M (-$2.08M)

20% less repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 30

Holders
96
Holders Change
+9
Holders Change %
+10.34%
% of All Funds
1.17%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
22
Increased
24
Reduced
30
Closed
10
Calls
$745K
Puts
$102K
Net Calls
+$643K
Net Calls Change
-$862K
Name Holding Trade Value Shares
Change
Change in
Stake
Connor, Clark & Lunn Investment Management (CC&L)
26
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$213K +$271K +67,959 New
Canada Pension Plan Investment Board
27
Canada Pension Plan Investment Board
Ontario, Canada
$208K +$263K +66,100 New
Goldman Sachs
28
Goldman Sachs
New York
$194K +$63.8K +16,034 +35%
SPS
29
Susquehanna Portfolio Strategies
Pennsylvania
$187K -$433K -108,808 -65%
Squarepoint
30
Squarepoint
New York
$173K +$164K +41,179 +295%
ECM
31
ExodusPoint Capital Management
New York
$149K +$189K +47,461 New
Barclays
32
Barclays
United Kingdom
$145K +$144K +36,053 +353%
AC
33
Avestar Capital
New York
$129K
Qube Research & Technologies (QRT)
34
Qube Research & Technologies (QRT)
United Kingdom
$125K +$159K +39,895 New
EGM
35
Engineers Gate Manager
New York
$111K +$100 +25 +0.1%
VF
36
Virtu Financial
New York
$108K +$137K +34,385 New
Two Sigma Advisers
37
Two Sigma Advisers
New York
$108K +$136K +34,245 New
GCM
38
Graham Capital Management
Connecticut
$99.6K -$92K -23,114 -42%
OCM
39
Ovata Capital Management
Hong Kong
$96.7K +$123K +30,800 New
CAPTRUST Financial Advisors
40
CAPTRUST Financial Advisors
North Carolina
$94.5K -$2.38K -597 -2%
KCFA
41
Key Client Fiduciary Advisors
New Jersey
$85.9K -$47.3K -11,885 -30%
Osaic Holdings
42
Osaic Holdings
Arizona
$85.2K -$27.2K -6,826 -20%
HighTower Advisors
43
HighTower Advisors
Illinois
$78.9K -$597 -150 -0.6%
T. Rowe Price Associates
44
T. Rowe Price Associates
Maryland
$77K +$97.6K +24,500 New
LPL Financial
45
LPL Financial
California
$73.2K +$15.7K +3,943 +20%
Group One Trading
46
Group One Trading
Illinois
$69.8K +$88.5K +22,239 New
VPIM
47
Vanguard Personalized Indexing Management
California
$62.3K -$1.27K -318 -2%
LIP
48
Lighthouse Investment Partners
Florida
$58.8K +$74.5K +18,720 New
HSBC Holdings
49
HSBC Holdings
United Kingdom
$54.2K
QC
50
Quadrature Capital
United Kingdom
$53.8K +$68.2K +17,121 New

AGEN Hedge Fund Activity: Q4 2025 in Review

96 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Agenus (AGEN) for Q4 2025, worth a combined $31.8M — down 6.1% from $33.9M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new AGEN positions and 10 closed out — a net gain of 12 holders — while 24 added to existing stakes and 30 trimmed.

The largest buyer was Renaissance Technologies, adding an estimated $1.9M. The largest seller was Bank of America, cutting an estimated $1.42M.

  • 96 institutional investors held Agenus (AGEN) as of Q4 2025, up from 87 in Q3 2025.
  • Funds reported $31.8M of Agenus stock for Q4 2025, down 6.1% quarter-over-quarter.
  • 22 funds opened new Agenus positions in Q4 2025 and 10 closed out, a net change of +12 holders.
  • The largest Agenus buyer in Q4 2025 was Renaissance Technologies, an estimated $1.9M added.
  • The largest Agenus seller in Q4 2025 was Bank of America, an estimated $1.42M sold.

Based on aggregated 13F filings for Q4 2025.