|
1
|
|
$163M
|
+$166M
|
+5,477,958
|
New
|
|
|
2
|
Deerfield Management
New York
|
$129M
|
+$132M
|
+4,341,799
|
New
|
|
|
3
|
Capital World Investors
Los Angeles,
California
|
$30.9M
|
+$31.4M
|
+1,035,935
|
New
|
|
|
4
|
Opaleye Management
Boston,
Massachusetts
|
$22.4M
|
+$22.8M
|
+749,990
|
New
|
|
|
5
|
|
$20.3M
|
+$20.6M
|
+679,986
|
New
|
|
|
6
|
American Financial Group
Cincinnati,
Ohio
|
$17.9M
|
+$18.2M
|
+599,990
|
New
|
|
|
7
|
Pura Vida Investments
New York
|
$15.9M
|
+$16.2M
|
+534,998
|
New
|
|
|
8
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$15.9M
|
+$16.2M
|
+532,158
|
New
|
|
|
9
|
Massachusetts Financial Services
Boston,
Massachusetts
|
$14M
|
+$14.3M
|
+470,796
|
New
|
|
|
10
|
|
$13.5M
|
+$13.7M
|
+451,834
|
New
|
|
|
11
|
Waddell & Reed Financial
Overland Park,
Kansas
|
$13.4M
|
+$13.7M
|
+449,647
|
New
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$11.9M
|
+$12.2M
|
+401,041
|
New
|
|
|
13
|
Wells Fargo
San Francisco,
California
|
$11M
|
+$11.2M
|
+370,136
|
New
|
|
|
14
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$9.55M
|
+$9.73M
|
+320,627
|
New
|
|
|
15
|
American Century Companies
Kansas City,
Missouri
|
$9.05M
|
+$9.22M
|
+303,703
|
New
|
|
|
16
|
|
$8.64M
|
+$8.8M
|
+290,000
|
New
|
|
|
17
|
Millennium Management
New York
|
$8.57M
|
+$8.73M
|
+287,534
|
New
|
|
|
18
|
Novo Holdings A/S
Hellerup,
Denmark
|
$7.6M
|
+$7.74M
|
+255,000
|
New
|
|
|
19
|
Ameriprise
Minneapolis,
Minnesota
|
$5.82M
|
+$5.92M
|
+195,145
|
New
|
|
|
20
|
Index Venture Associates V
St. Helier, Channel Islands,
Jersey
|
$4.88M
|
+$4.97M
|
+163,574
|
New
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$4.51M
|
+$4.6M
|
+151,378
|
New
|
|
|
22
|
State Street
Boston,
Massachusetts
|
$3.59M
|
+$3.66M
|
+120,438
|
New
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$3.46M
|
+$3.52M
|
+116,045
|
New
|
|
|
24
|
Citadel Advisors
Miami,
Florida
|
$2.82M
|
+$2.87M
|
+94,502
|
New
|
|
|
25
|
Parian Global Management
Pound Ridge,
New York
|
$2.5M
|
+$2.55M
|
+84,000
|
New
|
|