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ADC Therapeutics

106 hedge funds and large institutions have $271M invested in ADC Therapeutics in 2025 Q3 according to their latest regulatory filings, with 23 funds opening new positions, 31 increasing their positions, 22 reducing their positions, and 3 closing their positions.

New
Increased
Maintained
Reduced
Closed

667% more first-time investments, than exits

New positions opened: 23 | Existing positions closed: 3

49% more capital invested

Capital invested by funds: $182M → $271M (+$89.2M)

41% more repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 22

23% more funds holding

Funds holding: 86106 (+20)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

8.22% less ownership

Funds ownership: 68.52%60.3% (-8.2%)

56% less call options, than puts

Call options by funds: $161K | Put options by funds: $364K

Holders
106
Holders Change
+20
Holders Change %
+23.26%
% of All Funds
1.39%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
23
Increased
31
Reduced
22
Closed
3
Calls
$161K
Puts
$364K
Net Calls
-$203K
Net Calls Change
-$115K
Name Holding Trade Value Shares
Change
Change in
Stake
RG
1
Redmile Group
California
$62.7M
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$32.5M +$1.17M +371,993 +5%
PM
3
Prosight Management
Texas
$29.9M -$9.44M -2,995,468 -29%
O
4
OrbiMed
New York
$23.6M
BlackRock
5
BlackRock
New York
$18M -$30.4K -9,644 -0.2%
Morgan Stanley
6
Morgan Stanley
New York
$14.7M +$1.97M +623,494 +20%
NCM
7
Nantahala Capital Management
Connecticut
$9.07M
Goldman Sachs
8
Goldman Sachs
New York
$6.38M +$163K +51,832 +3%
TCM
9
TCG Crossover Management
California
$5.56M +$4.38M +1,390,175 New
Bank of America
10
Bank of America
North Carolina
$5.45M -$2.64M -837,769 -38%
LCM
11
Lynx1 Capital Management
Puerto Rico
$5.3M +$4.18M +1,325,848 New
State Street
12
State Street
Massachusetts
$5.18M +$194K +61,468 +5%
PIM
13
Platinum Investment Management
Australia
$4.63M -$727K -230,544 -17%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$3.45M +$13K +4,138 +0.5%
Citadel Advisors
15
Citadel Advisors
Florida
$3.28M +$2.5M +791,709 +2,729%
BOCH
16
Blue Owl Capital Holdings
New York
$2.93M
Millennium Management
17
Millennium Management
New York
$2.81M +$1M +317,945 +83%
BNP Paribas Financial Markets
18
BNP Paribas Financial Markets
France
$2.75M +$286K +90,679 +15%
VCG
19
Vantage Consulting Group
Virginia
$2.73M
OM
20
Opaleye Management
Massachusetts
$2.73M +$2.15M +682,529 New
Vanguard Group
21
Vanguard Group
Pennsylvania
$2.38M +$105K +33,431 +6%
PAM
22
Panagora Asset Management
Massachusetts
$2.18M +$860K +272,902 +101%
Jane Street
23
Jane Street
New York
$1.95M +$1.54M +487,868 New
Northern Trust
24
Northern Trust
Illinois
$1.67M -$29.4K -9,319 -2%
JP Morgan Chase
25
JP Morgan Chase
New York
$1.32M +$934K +296,350 +865%

ADCT Hedge Fund Activity: Q3 2025 in Review

106 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in ADC Therapeutics (ADCT) for Q3 2025, worth a combined $271M — up 49% from $182M a quarter earlier.

Buyers outnumbered sellers: 23 funds opened new ADCT positions and 3 closed out — a net gain of 20 holders — while 31 added to existing stakes and 22 trimmed.

The largest buyer was TCG Crossover Management, opening a new position worth an estimated $4.38M. The largest seller was Prosight Management, cutting an estimated $9.44M.

  • 106 institutional investors held ADC Therapeutics (ADCT) as of Q3 2025, up from 86 in Q2 2025.
  • Funds reported $271M of ADC Therapeutics stock for Q3 2025, up 49% quarter-over-quarter.
  • 23 funds opened new ADC Therapeutics positions in Q3 2025 and 3 closed out, a net change of +20 holders.
  • The largest ADC Therapeutics buyer in Q3 2025 was TCG Crossover Management, an estimated $4.38M added.
  • The largest ADC Therapeutics seller in Q3 2025 was Prosight Management, an estimated $9.44M sold.

Based on aggregated 13F filings for Q3 2025.