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ACOG

Alpha Cognition

27 hedge funds and large institutions have $64.4M invested in Alpha Cognition in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 11 increasing their positions, 3 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

267% more repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 3

75% more capital invested

Capital invested by funds: $36.7M → $64.4M (+$27.7M)

4% less funds holding

Funds holding: 2827 (-1)

13% less first-time investments, than exits

New positions opened: 7 | Existing positions closed: 8

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
27
Holders Change
-1
Holders Change %
-3.57%
% of All Funds
0.33%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
7
Increased
11
Reduced
3
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
OM
1
Opaleye Management
Massachusetts
$13.5M +$12.4M +1,955,642 +1,698%
SCM
2
Solas Capital Management
Connecticut
$12.8M +$4.33M +685,860 +53%
AIC
3
AWM Investment Company
New York
$10.9M +$3.64M +576,516 +53%
CCC
4
Cable Car Capital
California
$6.89M +$1.21M +191,210 +22%
IC
5
Ikarian Capital
Texas
$6.87M +$695K +110,000 +12%
SFM
6
Sphera Funds Management
Israel
$3.69M +$1.45M +228,864 +68%
Alyeska Investment Group
7
Alyeska Investment Group
Illinois
$2.37M +$2.31M +365,000 New
BFM
8
Boothbay Fund Management
New York
$1.67M -$224K -35,475 -12%
AC
9
Aristides Capital
Kentucky
$1.4M +$316K +50,000 +30%
CF
10
Cantor Fitzgerald
New York
$1.06M +$1.03M +163,431 New
Citadel Advisors
11
Citadel Advisors
Florida
$770K +$748K +118,421 New
SDJVC
12
St. Denis J. Villere & Co
Louisiana
$480K +$54.4K +8,617 +13%
Tudor Investment Corp
13
Tudor Investment Corp
Connecticut
$400K
Two Sigma Investments
14
Two Sigma Investments
New York
$374K +$220K +34,844 +153%
Marshall Wace
15
Marshall Wace
United Kingdom
$346K -$120K -19,009 -26%
ACM
16
ACT Capital Management
Pennsylvania
$335K +$325K +51,500 New
Susquehanna International Group
17
Susquehanna International Group
Pennsylvania
$226K +$219K +34,706 New
BAM
18
Berkshire Asset Management
Pennsylvania
$129K +$12.6K +2,000 +11%
QC
19
Quadrature Capital
United Kingdom
$81.3K -$7.21K -1,141 -8%
Geode Capital Management
20
Geode Capital Management
Massachusetts
$77.9K
GAA
21
Green Alpha Advisors
Colorado
$72.3K +$70.3K +11,126 New
National Bank of Canada
22
National Bank of Canada
Quebec, Canada
$34.4K
UBS Group
23
UBS Group
Switzerland
$6.03K +$4.96K +786 +557%
AF
24
Allworth Financial
California
$4.88K +$4.74K +750 New
SPIA
25
Steward Partners Investment Advisory
New York
$1.3K

ACOG Hedge Fund Activity: Q4 2025 in Review

27 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Alpha Cognition (ACOG) for Q4 2025, worth a combined $64.4M — up 75% from $36.7M a quarter earlier.

Sellers outnumbered buyers: 8 funds closed out of ACOG and 7 opened new positions — a net loss of 1 holder — while 3 trimmed existing stakes and 11 added.

The largest buyer was Opaleye Management, adding an estimated $12.4M. The largest seller was Corsair Capital Management, exiting entirely with an estimated $878K sold.

  • 27 institutional investors held Alpha Cognition (ACOG) as of Q4 2025, down from 28 in Q3 2025.
  • Funds reported $64.4M of Alpha Cognition stock for Q4 2025, up 75% quarter-over-quarter.
  • 7 funds opened new Alpha Cognition positions in Q4 2025 and 8 closed out, a net change of -1 holder.
  • The largest Alpha Cognition buyer in Q4 2025 was Opaleye Management, an estimated $12.4M added.
  • The largest Alpha Cognition seller in Q4 2025 was Corsair Capital Management, an estimated $878K sold.

Based on aggregated 13F filings for Q4 2025.