Alpha Cognition
ACOG
27 hedge funds and large institutions have $64.4M invested in Alpha Cognition in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 11 increasing their positions, 3 reducing their positions, and 8 closing their positions.
267% more repeat investments, than reductions
Existing positions increased: 11 | Existing positions reduced: 3
75% more capital invested
Capital invested by funds: $36.7M → $64.4M (+$27.7M)
4% less funds holding
Funds holding: 28 → 27 (-1)
13% less first-time investments, than exits
New positions opened: 7 | Existing positions closed: 8
50% less funds holding in top 10
Funds holding in top 10: 2 → 1 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
OM
Opaleye Management
Boston,
Massachusetts
|
+$12.4M |
| 2 |
SCM
Solas Capital Management
Darien,
Connecticut
|
+$4.33M |
| 3 |
AIC
AWM Investment Company
New York
|
+$3.64M |
| 4 |
Alyeska Investment Group
Chicago,
Illinois
|
+$2.31M |
| 5 |
SFM
Sphera Funds Management
Tel Aviv,
Israel
|
+$1.45M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
CCM
Corsair Capital Management
New York
|
-$878K |
| 2 |
CCM
Connective Capital Management
Palo Alto,
California
|
-$312K |
| 3 |
SIC
Salem Investment Counselors
Winston Salem,
North Carolina
|
-$296K |
| 4 |
BFM
Boothbay Fund Management
New York
|
-$224K |
| 5 |
ZIG
Zullo Investment Group
Scranton,
Pennsylvania
|
-$127K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
26
Royal Bank of Canada
Toronto,
Ontario, Canada
| $1K | – | – | – |
|
27
PNC Financial Services Group
Pittsburgh,
Pennsylvania
| $780 | – | – | – |
|
|
CCM
28
Corsair Capital Management
New York
| – | -$878K | -134,898 | Closed |
|
|
CCM
29
Connective Capital Management
Palo Alto,
California
| – | -$312K | -47,931 | Closed |
|
|
SIC
30
Salem Investment Counselors
Winston Salem,
North Carolina
| – | -$296K | -45,402 | Closed |
|
|
ZIG
31
Zullo Investment Group
Scranton,
Pennsylvania
| – | -$127K | -19,500 | Closed |
|
32
Millennium Management
New York
| – | -$112K | -17,250 | Closed |
|
|
TRCT
33
Tower Research Capital (TRC)
New York
| – | -$10.7K | -1,648 | Closed |
|
34
Morgan Stanley
New York
| – | -$5.47K | -840 | Closed |
|
35
Jones Financial Companies
Des Peres,
Missouri
| – | -$1.42K | -200 | Closed |
|
ACOG Hedge Fund Activity: Q4 2025 in Review
27 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Alpha Cognition (ACOG) for Q4 2025, worth a combined $64.4M — up 75% from $36.7M a quarter earlier.
Sellers outnumbered buyers: 8 funds closed out of ACOG and 7 opened new positions — a net loss of 1 holder — while 3 trimmed existing stakes and 11 added.
The largest buyer was Opaleye Management, adding an estimated $12.4M. The largest seller was Corsair Capital Management, exiting entirely with an estimated $878K sold.
- 27 institutional investors held Alpha Cognition (ACOG) as of Q4 2025, down from 28 in Q3 2025.
- Funds reported $64.4M of Alpha Cognition stock for Q4 2025, up 75% quarter-over-quarter.
- 7 funds opened new Alpha Cognition positions in Q4 2025 and 8 closed out, a net change of -1 holder.
- The largest Alpha Cognition buyer in Q4 2025 was Opaleye Management, an estimated $12.4M added.
- The largest Alpha Cognition seller in Q4 2025 was Corsair Capital Management, an estimated $878K sold.
Based on aggregated 13F filings for Q4 2025.