|
1
|
RA Capital Management
Boston,
Massachusetts
|
$56.3M
|
+$8.51M
|
+1,600,000
|
+13%
|
|
|
2
|
|
$54.1M
|
–
|
–
|
–
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$36.9M
|
+$1.46M
|
+274,451
|
+3%
|
|
|
4
|
BlackRock Fund Advisors
San Francisco,
California
|
$22.3M
|
+$3.33M
|
+626,133
|
+13%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$21.2M
|
+$7.79M
|
+1,465,723
|
+40%
|
|
|
6
|
Janus Henderson Investors US
Denver,
Colorado
|
$19.2M
|
-$5.28M
|
-993,649
|
-18%
|
|
|
7
|
|
$18.4M
|
-$5.57M
|
-1,047,198
|
-19%
|
|
|
8
|
BlackRock Institutional Trust
San Francisco,
California
|
$16M
|
+$2.45M
|
+460,419
|
+14%
|
|
|
9
|
Numeric Investors
Boston,
Massachusetts
|
$11.3M
|
+$9.74M
|
+1,832,386
|
+205%
|
|
|
10
|
BVF Inc
San Francisco,
California
|
$10M
|
+$12.9M
|
+2,423,300
|
New
|
|
|
11
|
|
$9.87M
|
+$10.8M
|
+2,027,775
|
+559%
|
|
|
12
|
Baker Bros. Advisors
New York
|
$7.67M
|
-$3.29M
|
-618,878
|
-25%
|
|
|
13
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$7.4M
|
+$138K
|
+26,047
|
+1%
|
|
|
14
|
Wellington Management Group
Boston,
Massachusetts
|
$6.9M
|
-$403K
|
-75,794
|
-4%
|
|
|
15
|
Fidelity Investments
Boston,
Massachusetts
|
$6.28M
|
-$9.46M
|
-1,779,867
|
-54%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$5.96M
|
+$44.1K
|
+8,292
|
+0.6%
|
|
|
17
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$5.68M
|
+$314K
|
+59,000
|
+4%
|
|
|
18
|
BB Biotech
Schaffhausen,
Switzerland
|
$5.28M
|
–
|
–
|
–
|
|
|
19
|
Millennium Management
New York
|
$4.67M
|
+$5.67M
|
+1,067,461
|
+1,682%
|
|
|
20
|
|
$4.62M
|
–
|
–
|
–
|
|
|
21
|
Spark Investment Management
New York
|
$4.04M
|
+$4.74M
|
+892,600
|
+1,038%
|
|
|
22
|
Renaissance Technologies
New York
|
$3.9M
|
+$2.09M
|
+392,589
|
+71%
|
|
|
23
|
Teachers Advisors
New York
|
$3.9M
|
+$944K
|
+177,537
|
+23%
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$3.76M
|
-$327K
|
-61,490
|
-6%
|
|
|
25
|
|
$3.5M
|
+$85.5K
|
+16,091
|
+2%
|
|
