|
1
|
|
$66.6M
|
–
|
–
|
–
|
|
|
2
|
|
$37.9M
|
–
|
–
|
–
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$31.8M
|
+$55.5M
|
+222,544
|
New
|
|
|
4
|
Cowen and Company
New York
|
$28.1M
|
+$10.9M
|
+43,773
|
+29%
|
|
|
5
|
|
$22.8M
|
+$6.8M
|
+27,239
|
+21%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$20.4M
|
+$5.09M
|
+20,395
|
+17%
|
|
|
7
|
Abingworth
London,
United Kingdom
|
$18.9M
|
–
|
–
|
–
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$15.1M
|
+$2.99M
|
+11,989
|
+13%
|
|
|
9
|
|
$14.6M
|
-$446K
|
-1,789
|
-2%
|
|
|
10
|
Polar Capital Holdings
London,
United Kingdom
|
$11.3M
|
-$465K
|
-1,865
|
-2%
|
|
|
11
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$11M
|
-$3.45M
|
-13,834
|
-15%
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$7.18M
|
+$12.5M
|
+50,222
|
New
|
|
|
13
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$6.52M
|
–
|
–
|
–
|
|
|
14
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$6.11M
|
+$112K
|
+450
|
+1%
|
|
|
15
|
DAFNA Capital Management
Los Angeles,
California
|
$5.65M
|
-$4.74M
|
-19,013
|
-33%
|
|
|
16
|
Cormorant Asset Management
Boston,
Massachusetts
|
$5.36M
|
-$12.5M
|
-50,000
|
-57%
|
|
|
17
|
Tang Capital Management
San Diego,
California
|
$5.36M
|
+$9.36M
|
+37,500
|
New
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$5.28M
|
+$806K
|
+3,229
|
+10%
|
|
|
19
|
Decheng Capital Management III (Cayman)
Grand Cayman,
Cayman Islands
|
$5.19M
|
–
|
–
|
–
|
|
|
20
|
Fidelity Investments
Boston,
Massachusetts
|
$5.04M
|
-$3.83M
|
-15,363
|
-30%
|
|
|
21
|
Foresite Capital Management V
Larkspur,
California
|
$4.99M
|
-$1.89M
|
-7,585
|
-18%
|
|
|
22
|
Citadel Advisors
Miami,
Florida
|
$3.42M
|
+$1.88M
|
+7,533
|
+46%
|
|
|
23
|
|
$2.58M
|
-$1.67M
|
-6,679
|
-27%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$2.38M
|
+$397K
|
+1,592
|
+11%
|
|
|
25
|
Rafferty Asset Management
New York
|
$1.63M
|
+$788K
|
+3,158
|
+38%
|
|
