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143 hedge funds and large institutions have $426M invested in Absci in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 51 increasing their positions, 32 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

448% more call options, than puts

Call options by funds: $5.93M | Put options by funds: $1.08M

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

59% more repeat investments, than reductions

Existing positions increased: 51 | Existing positions reduced: 32

45% more capital invested

Capital invested by funds: $294M → $426M (+$132M)

16.54% more ownership

Funds ownership: 64.65%81.19% (+17%)

10% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 20

1% more funds holding

Funds holding: 142143 (+1)

Holders
143
Holders Change
+1
Holders Change %
+0.7%
% of All Funds
1.73%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
22
Increased
51
Reduced
32
Closed
20
Calls
$5.93M
Puts
$1.08M
Net Calls
+$4.85M
Net Calls Change
+$4.43M

ABSI Hedge Fund Activity: Q4 2025 in Review

143 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Absci (ABSI) for Q4 2025, worth a combined $426M — up 45% from $294M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new ABSI positions and 20 closed out — a net gain of 2 holders — while 51 added to existing stakes and 32 trimmed.

The largest buyer was State Street, adding an estimated $14.3M. The largest seller was Heights Capital Management, cutting an estimated $3.41M.

  • 143 institutional investors held Absci (ABSI) as of Q4 2025, up from 142 in Q3 2025.
  • Funds reported $426M of Absci stock for Q4 2025, up 45% quarter-over-quarter.
  • 22 funds opened new Absci positions in Q4 2025 and 20 closed out, a net change of +2 holders.
  • The largest Absci buyer in Q4 2025 was State Street, an estimated $14.3M added.
  • The largest Absci seller in Q4 2025 was Heights Capital Management, an estimated $3.41M sold.

Based on aggregated 13F filings for Q4 2025.