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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
HLT icon
426
Hilton Worldwide
HLT
$72.6B
$11.4M 0.04%
39,708
+8,624
+28% +$2.35M
APO icon
427
Apollo Global Management
APO
$73.4B
$11.4M 0.04%
78,704
+17,898
+29% +$2.38M
GMAB icon
428
Genmab
GMAB
$17.7B
$11.4M 0.04%
369,188
-89,988
-20% -$2.8M
BIRK icon
429
Birkenstock
BIRK
$6.84B
$11.3M 0.04%
276,487
– –
CE icon
430
Celanese
CE
$4.96B
$11.2M 0.04%
265,459
+85,139
+47% +$3.47M
SHCO
431
DELISTED
Soho House & Co
SHCO
$11.1M 0.04%
1,237,472
-27,528
-2% -$244K
BL icon
432
BlackLine
BL
$1.75B
$11.1M 0.04%
+200,378
New +$11M
CTAS icon
433
Cintas
CTAS
$80B
$11M 0.04%
58,651
+13,378
+30% +$2.52M
INBX icon
434
Inhibrx
INBX
$1.25B
$11M 0.04%
139,479
-197,111
-59% -$13.4M
IMCR icon
435
Immunocore
IMCR
$1.66B
$11M 0.04%
316,685
+109,247
+53% +$3.86M
PODD icon
436
Insulet
PODD
$9.51B
$11M 0.04%
38,616
+1,469
+4% +$459K
JHG
437
DELISTED
Janus Henderson
JHG
$10.9M 0.04%
+230,000
New +$10.2M
MSI icon
438
Motorola Solutions
MSI
$77.6B
$10.9M 0.04%
28,418
-84,747
-75% -$34.1M
TFC icon
439
Truist Financial
TFC
$64.5B
$10.7M 0.04%
218,450
+48,034
+28% +$2.21M
SLG icon
440
SL Green Realty
SLG
$3.86B
$10.7M 0.04%
+234,343
New +$11.6M
SEPN
441
Septerna Inc
SEPN
$1.76B
$10.7M 0.04%
385,310
+102,725
+36% +$2.45M
PWR icon
442
Quanta Services
PWR
$102B
$10.7M 0.04%
25,440
+5,747
+29% +$2.53M
FDX icon
443
FedEx
FDX
$74.8B
$10.7M 0.04%
37,168
+15,187
+69% +$3.99M
NEM icon
444
Newmont
NEM
$110B
$10.7M 0.04%
107,430
+87,712
+445% +$7.92M
SABS icon
445
SAB Biotherapeutics
SABS
$285M
$10.7M 0.04%
2,850,881
– –
VKTX icon
446
Viking Therapeutics
VKTX
$3.88B
$10.6M 0.04%
302,032
+38
+0% +$1.35K
PR
447
Permian Resources
PR
$17.1B
$10.6M 0.04%
752,364
-3,166,334
-81% -$42.5M
AEP icon
448
American Electric Power
AEP
$68.2B
$10.5M 0.04%
91,317
+20,638
+29% +$2.44M
ROK icon
449
Rockwell Automation
ROK
$49.1B
$10.5M 0.04%
+27,032
New +$10.2M
ABUS icon
450
Arbutus Biopharma
ABUS
$883M
$10.5M 0.04%
2,186,553
+20,951
+1% +$94.2K
16 17
18
19 20

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.