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Two Sigma Securities’s TherapeuticsMD TXMD Stock Holding History

Two Sigma Securities’s Portfolio TXMD Stock Details TXMD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-11,967
Closed -$12.9K – 2028
2025
Q3 		$12.9K Buy
11,967
+1,531
+15% +$1.72K ﹤0.01% 1188
2025
Q2 		$12.1K Sell
10,436
-2,729
-21% -$3.31K ﹤0.01% 1288
2025
Q1 		$12.2K Buy
+13,165
New +$13.1K ﹤0.01% 1195
2024
Q3 		– Sell
-14,359
Closed -$23.1K – 3643
2024
Q2 		$23.1K Buy
+14,359
New +$29K ﹤0.01% 2670
2022
Q3 		– Sell
-10,368
Closed -$103K – 3114
2022
Q2 		$103K Buy
10,368
+10,014
+2,829% +$95.6K ﹤0.01% 1748
2022
Q1 		$7K Buy
+354
New +$5.57K ﹤0.01% 2056
2021
Q4 		– Sell
-1,321
Closed -$49K – 2052
2021
Q3 		$49K Buy
+1,321
New +$58.6K ﹤0.01% 1386
2021
Q2 		– Sell
-1,819
Closed -$122K – 1716
2021
Q1 		$122K Buy
1,819
+702
+63% +$55K 0.01% 683
2020
Q4 		$68K Buy
+1,117
New +$76.3K ﹤0.01% 1540
2020
Q3 		– Sell
-1,055
Closed -$66K – 1666
2020
Q2 		$66K Buy
1,055
+204
+24% +$11.9K ﹤0.01% 1240
2020
Q1 		$45K Sell
851
-1,157
-58% -$115K ﹤0.01% 1192
2019
Q4 		$243K Buy
2,008
+1,606
+400% +$231K ﹤0.01% 1947
2019
Q3 		$73K Sell
402
-2,136
-84% -$301K ﹤0.01% 1956
2019
Q2 		$330K Buy
+2,538
New +$455K ﹤0.01% 1397
2018
Q2 		– Sell
-250
Closed -$61K – 3020
2018
Q1 		$61K Buy
+250
New +$70.1K ﹤0.01% 2489

Other funds holding TXMD

RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
CC
Clearline Capital New York $1.93B AUM 38.13% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
TC
Tejara Capital London, United Kingdom $303M AUM 5.43% 1-Year Est. Return
ACM
ADAR1 Capital Management Austin, Texas $1.7B AUM 340.85% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return
Susquehanna International Group
Susquehanna International Group Bala Cynwyd, Pennsylvania $893B AUM 36.07% 1-Year Est. Return

Two Sigma Securities's TXMD Position: Q4 2025 in Review

Two Sigma Securities sold out of TherapeuticsMD (TXMD) in Q4 2025, closing a stake of 11,967 shares — an estimated $12.9K sold.

Two Sigma Securities first reported a position in TXMD in Q1 2018 and held it in 15 quarters. The position peaked at $330K in Q2 2019. 44 funds tracked by Wall St. Rank hold TXMD as of Q4 2025.

  • Two Sigma Securities reported no remaining TherapeuticsMD position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Securities sold 11,967 TherapeuticsMD shares in Q4 2025, an estimated $12.9K.
  • Two Sigma Securities first reported a position in TherapeuticsMD in Q1 2018 and held it in 15 quarters.
  • Two Sigma Securities's TherapeuticsMD position peaked at $330K in Q2 2019.
  • 44 funds tracked by Wall St. Rank held TherapeuticsMD as of Q4 2025.

Based on Two Sigma Securities's 13F filing for Q4 2025, filed 17 Feb 2026.