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Two Sigma Securities’s Tiziana Life Sciences TLSA Stock Holding History

Two Sigma Securities’s Portfolio TLSA Stock Details TLSA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-17,458
Closed -$27.6K – 1989
2025
Q2 		$27.6K Sell
17,458
-2,934
-14% -$3.92K ﹤0.01% 1165
2025
Q1 		$22K Buy
+20,392
New +$19.9K ﹤0.01% 1087
2024
Q1 		– Sell
-11,349
Closed -$6.36K – 3645
2023
Q4 		$6.36K Buy
+11,349
New +$7.16K ﹤0.01% 2868
2021
Q4 		– Sell
-18,578
Closed -$27K – 2039
2021
Q3 		$27K Buy
+18,578
New +$34.3K ﹤0.01% 1442

Other funds holding TLSA

DIG
Dauntless Investment Group Etna, New Hampshire $151M AUM 76.14% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
ZF
Zhang Financial Portage, Michigan $3.42B AUM 23.04% 1-Year Est. Return
Kovitz Investment Group Partners
Kovitz Investment Group Partners Chicago, Illinois $4.31B AUM 20.41% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
HSBC Holdings
HSBC Holdings London, United Kingdom $192B AUM 27.2% 1-Year Est. Return
Susquehanna International Group
Susquehanna International Group Bala Cynwyd, Pennsylvania $893B AUM 36.07% 1-Year Est. Return
EL
EWA LLC Pittsbugh, Pennsylvania $548M AUM 35.14% 1-Year Est. Return

Two Sigma Securities's TLSA Position: Q3 2025 in Review

Two Sigma Securities sold out of Tiziana Life Sciences (TLSA) in Q3 2025, closing a stake of 17,458 shares — an estimated $27.6K sold.

Two Sigma Securities first reported a position in TLSA in Q3 2021 and held it in 4 quarters. The position peaked at $27.6K in Q2 2025. 31 funds tracked by Wall St. Rank hold TLSA as of Q3 2025.

  • Two Sigma Securities reported no remaining Tiziana Life Sciences position as of Q3 2025 after selling out during the quarter.
  • Two Sigma Securities sold 17,458 Tiziana Life Sciences shares in Q3 2025, an estimated $27.6K.
  • Two Sigma Securities first reported a position in Tiziana Life Sciences in Q3 2021 and held it in 4 quarters.
  • Two Sigma Securities's Tiziana Life Sciences position peaked at $27.6K in Q2 2025.
  • 31 funds tracked by Wall St. Rank held Tiziana Life Sciences as of Q3 2025.

Based on Two Sigma Securities's 13F filing for Q3 2025, filed 14 Nov 2025.