TSS
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Two Sigma Securities’s Talphera TLPH Stock Holding History

Two Sigma Securities’s Portfolio TLPH Stock Details TLPH Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$13.9K Buy
+18,663
New +$16.9K ﹤0.01% 1431
2025
Q3 		– Sell
-11,171
Closed -$5.14K – 1988
2025
Q2 		$5.14K Buy
+11,171
New +$5.56K ﹤0.01% 1357
2024
Q4 		– Sell
-20,157
Closed -$17.3K – 3150
2024
Q3 		$17.3K Sell
20,157
-18,787
-48% -$17.2K ﹤0.01% 2519
2024
Q2 		$34.7K Buy
+38,944
New +$39.7K ﹤0.01% 2621
2022
Q4 		– Sell
-2,030
Closed -$8K – 3258
2022
Q3 		$8K Buy
2,030
+1,450
+250% +$7.59K ﹤0.01% 2432
2022
Q2 		$3K Sell
580
-1,566
-73% -$7.29K ﹤0.01% 2129
2022
Q1 		$12K Buy
+2,146
New +$18.2K ﹤0.01% 2037
2021
Q4 		– Sell
-1,175
Closed -$24K – 2037
2021
Q3 		$24K Buy
+1,175
New +$26.9K ﹤0.01% 1449
2019
Q2 		– Sell
-533
Closed -$37K – 2420
2019
Q1 		$37K Buy
+533
New +$31.1K ﹤0.01% 1637
2018
Q2 		– Sell
-743
Closed -$31K – 3009
2018
Q1 		$31K Sell
743
-1,041
-58% -$41.1K ﹤0.01% 2543
2017
Q4 		$72K Buy
1,784
+930
+109% +$45.4K ﹤0.01% 1488
2017
Q3 		$79K Buy
+854
New +$53.2K 0.01% 696
2017
Q1 		– Sell
-876
Closed -$46K – 1109
2016
Q4 		$46K Buy
+876
New +$53.9K 0.02% 604
2016
Q2 		– Sell
-680
Closed -$42K – 515
2016
Q1 		$42K Buy
+680
New +$47.2K 0.05% 211

Other funds holding TLPH

ACM
AIGH Capital Management Baltimore, Maryland $733M AUM 327.32% 1-Year Est. Return
RSCM
Rock Springs Capital Management Baltimore, Maryland $1.7B AUM 93.03% 1-Year Est. Return
NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
RA
Rosalind Advisors Toronto, Ontario, Canada $249M AUM 80.12% 1-Year Est. Return
BL
Bleichroeder LP New York $579M AUM 94.36% 1-Year Est. Return
CF
Cantor Fitzgerald New York $6.78B AUM 29.01% 1-Year Est. Return
EAM
Empery Asset Management New York $83M AUM
CM
Caption Management Oklahoma City, Oklahoma $17.1B AUM 70.99% 1-Year Est. Return
AC
Almitas Capital Santa Monica, California $443M AUM 42.36% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Two Sigma Securities's TLPH Position: Q1 2026 in Review

Two Sigma Securities opened a new position in Talphera (TLPH) in Q1 2026: 18,663 shares worth $13.9K. The stake represents ﹤0.01% of the portfolio and ranks #1431 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in TLPH as recently as Q2 2025.

Two Sigma Securities first reported a position in TLPH in Q1 2016 and has held it in 14 quarters since. The position peaked at $79K in Q3 2017. 45 funds tracked by Wall St. Rank hold TLPH as of Q1 2026.

  • Two Sigma Securities held 18,663 shares of Talphera worth $13.9K as of Q1 2026.
  • Talphera was a new Two Sigma Securities position in Q1 2026.
  • Talphera made up ﹤0.01% of Two Sigma Securities's portfolio in Q1 2026, its #1431 holding.
  • Two Sigma Securities first reported a position in Talphera in Q1 2016 and has held it in 14 quarters since.
  • Two Sigma Securities's Talphera position peaked at $79K in Q3 2017.
  • 45 funds tracked by Wall St. Rank held Talphera as of Q1 2026.

Based on Two Sigma Securities's 13F filing for Q1 2026, filed 15 May 2026.