TSS
IRD

Two Sigma Securities’s Opus Genetics IRD Stock Holding History

Two Sigma Securities’s Portfolio IRD Stock Details IRD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-17,746
Closed -$29.3K – 2139
2025
Q3 		$29.3K Buy
+17,746
New +$22K ﹤0.01% 1068
2025
Q1 		– Sell
-16,202
Closed -$19.3K – 2357
2024
Q4 		$19.3K Buy
+16,202
New +$18.6K ﹤0.01% 1326
2019
Q2 		– Sell
-1,445
Closed -$35K – 2488
2019
Q1 		$35K Buy
+1,445
New +$47.9K ﹤0.01% 1638
2018
Q4 		– Sell
-283
Closed -$24K – 2935
2018
Q3 		$24K Buy
+283
New +$21.9K ﹤0.01% 2420
2018
Q1 		– Sell
-250
Closed -$24K – 3009
2017
Q4 		$24K Buy
+250
New +$25.4K ﹤0.01% 1614
2017
Q1 		– Sell
-227
Closed -$15K – 1155
2016
Q4 		$15K Sell
227
-159
-41% -$12.9K 0.01% 667
2016
Q3 		$39K Buy
+386
New +$46.6K 0.01% 571
2016
Q2 		– Sell
-31
Closed -$5K – 538
2016
Q1 		$5K Sell
31
-44
-59% -$7.32K 0.01% 278
2015
Q4 		$13K Buy
+75
New +$15.9K 0.02% 218

Other funds holding IRD

NCM
Nantahala Capital Management New Canaan, Connecticut $2.72B AUM 121.58% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
BCM
BIOS Capital Management Fort Worth, Texas $52.9M AUM 30.51% 1-Year Est. Return
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
MBAM
Mink Brook Asset Management West Palm Beach, Florida $179M AUM 37.68% 1-Year Est. Return
OM
Opaleye Management Boston, Massachusetts $759M AUM 124.8% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
BL
Bleichroeder LP New York $579M AUM 94.36% 1-Year Est. Return

Two Sigma Securities's IRD Position: Q4 2025 in Review

Two Sigma Securities sold out of Opus Genetics (IRD) in Q4 2025, closing a stake of 17,746 shares — an estimated $29.3K sold.

Two Sigma Securities first reported a position in IRD in Q4 2015 and held it in 9 quarters. The position peaked at $39K in Q3 2016. 59 funds tracked by Wall St. Rank hold IRD as of Q4 2025.

  • Two Sigma Securities reported no remaining Opus Genetics position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Securities sold 17,746 Opus Genetics shares in Q4 2025, an estimated $29.3K.
  • Two Sigma Securities first reported a position in Opus Genetics in Q4 2015 and held it in 9 quarters.
  • Two Sigma Securities's Opus Genetics position peaked at $39K in Q3 2016.
  • 59 funds tracked by Wall St. Rank held Opus Genetics as of Q4 2025.

Based on Two Sigma Securities's 13F filing for Q4 2025, filed 17 Feb 2026.