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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
+3.47%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$70.9B
AUM Growth
+$3.72B
Cap. Flow
+$541M
Cap. Flow %
0.76%
Top 10 Hldgs %
4.9%
Holding
4,545
New
899
Increased
1,598
Reduced
1,287
Closed
504

Sector Composition

Rank Sector Weight
1 Technology 15.53%
2 Financials 13%
3 Industrials 11.22%
4 Healthcare 10.29%
5 Consumer Discretionary 9.15%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
BEEM icon
3851
Beam Global
BEEM
$25.3M
$45.5K ﹤0.01%
30,342
-5,118
-14% -$11.8K
TVRD
3852
Tvardi Therapeutics
TVRD
$23.4M
$45.1K ﹤0.01%
+10,492
New +$94K
HEPS
3853
D-Market Electronic Services & Trading
HEPS
$990M
$44.5K ﹤0.01%
17,938
-3,400
-16% -$8.44K
SLAI
3854
DELISTED
SOLAI Ltd ADS
SLAI
$44.2K ﹤0.01%
9,420
+1,148
+14% +$14.8K
BAER icon
3855
Bridger Aerospace
BAER
$72.6M
$42.7K ﹤0.01%
+23,324
New +$40.7K
WRN
3856
Western Copper and Gold
WRN
$544M
$41.8K ﹤0.01%
+15,666
New +$36.2K
HUIZ
3857
Huize Holding Ltd
HUIZ
$16.8M
$41.3K ﹤0.01%
+14,712
New +$50.8K
GELS
3858
Gelteq Ltd
GELS
$5.98M
$41.1K ﹤0.01%
+51,361
New +$55.9K
MIRA icon
3859
MIRA Pharmaceuticals
MIRA
$31.1M
$40.8K ﹤0.01%
27,044
-18,659
-41% -$27.4K
IMUX icon
3860
Immunic
IMUX
$195M
$40.7K ﹤0.01%
7,619
+1,751
+30% +$12.8K
XLO icon
3861
Xilio Therapeutics
XLO
$60.3M
$39.7K ﹤0.01%
4,431
-1,840
-29% -$19.3K
NRSN icon
3862
NeuroSense Therapeutics
NRSN
$18M
$39.6K ﹤0.01%
51,545
+30,459
+144% +$32.1K
MBIO icon
3863
Mustang Bio
MBIO
$4.55M
$39.3K ﹤0.01%
+40,034
New +$52.9K
FNUC
3864
Frontier Nuclear and Minerals Inc
FNUC
$44.7M
$39K ﹤0.01%
13,011
-182
-1% -$688
MNTK icon
3865
Montauk Renewables
MNTK
$255M
$38.8K ﹤0.01%
23,215
+6,260
+37% +$12K
SKYE icon
3866
Skye Bioscience
SKYE
$18.3M
$38.8K ﹤0.01%
51,706
-40,612
-44% -$59.3K
THM
3867
International Tower Hill Mines
THM
$604M
$38.1K ﹤0.01%
+20,481
New +$38.1K
GGRP
3868
Glimpse Group
GGRP
$18.7M
$37.1K ﹤0.01%
40,114
-5,154
-11% -$6.55K
GXAI
3869
Gaxos.ai
GXAI
$9.13M
$37K ﹤0.01%
34,572
-22,173
-39% -$31.5K
SNTG icon
3870
Sentage Holdings
SNTG
$5.41M
$35.8K ﹤0.01%
+18,936
New +$45.6K
FTHM icon
3871
Fathom Holdings
FTHM
$25.2M
$34.5K ﹤0.01%
+34,200
New +$46.1K
AMST icon
3872
Amesite
AMST
$6.88M
$34.5K ﹤0.01%
18,270
+2,419
+15% +$6.82K
LCFY icon
3873
Locafy
LCFY
$4.28M
$33.8K ﹤0.01%
+12,083
New +$51.6K
OKUR
3874
OnKure Therapeutics
OKUR
$168M
$32.8K ﹤0.01%
11,320
-14,115
-55% -$42.3K
GRML
3875
Greenland Mines Ltd
GRML
$29.2M
$30.5K ﹤0.01%
105,548
+68,977
+189% +$33.1K

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Two Sigma Investments's Q4 2025 Portfolio in Review

As of Q4 2025, Two Sigma Investments held 4,545 positions worth $70.9B, up 5.5% from $67.2B the previous quarter. Its ten largest holdings account for 4.9% of the portfolio.

Two Sigma Investments's Q4 2025 filing shows 899 new, 1,598 increased, 1,287 reduced and 504 closed positions. Its largest new stake was Vanguard Real Estate ETF: 3,573,400 shares worth $316M. The largest sale was State Street Financial Select Sector SPDR ETF, an estimated $547M.

By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 16% a quarter earlier, followed by Financials and Industrials.

  • Two Sigma Investments's largest Q4 2025 buy was Vanguard Real Estate ETF: 3,573,400 shares worth $316M.
  • Two Sigma Investments added most to State Street Technology Select Sector SPDR ETF in Q4 2025, an estimated $395M increase.
  • Two Sigma Investments's biggest Q4 2025 reduction was State Street Financial Select Sector SPDR ETF, cutting an estimated $547M.
  • Two Sigma Investments fully exited State Street SPDR Dow Jones Industrial Average ETF Trust in Q4 2025, selling an estimated $240M.
  • Two Sigma Investments's ten largest holdings make up 4.9% of its $70.9B portfolio in Q4 2025.
  • Two Sigma Investments opened 899 new positions and closed 504 in Q4 2025.
  • Two Sigma Investments's portfolio value rose 5.5% quarter-over-quarter to $70.9B.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.