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Two Sigma Investments

Two Sigma Investments Portfolio holdings

AUM $124B
1-Year Est. Return 33.93%
This Fund
S&P 500
This Quarter Est. Return
+3.47%
1 Year Est. Return
+33.93%
3 Year Est. Return
+96.56%
5 Year Est. Return
+105.93%
10 Year Est. Return
+538.88%
AUM
$70.9B
AUM Growth
+$3.72B
Cap. Flow
+$541M
Cap. Flow %
0.76%
Top 10 Hldgs %
4.9%
Holding
4,545
New
899
Increased
1,598
Reduced
1,287
Closed
504

Sector Composition

Rank Sector Weight
1 Technology 15.53%
2 Financials 13%
3 Industrials 11.22%
4 Healthcare 10.29%
5 Consumer Discretionary 9.15%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
CNTA
2601
DELISTED
Centessa Pharmaceuticals
CNTA
$1.44M ﹤0.01%
57,444
HUMA icon
2602
Humacyte
HUMA
$194M
$1.43M ﹤0.01%
1,491,467
+124,883
+9% +$177K
TTGT icon
2603
TechTarget
TTGT
$278M
$1.42M ﹤0.01%
263,599
+97,197
+58% +$523K
VCEL icon
2604
Vericel Corp
VCEL
$2.31B
$1.42M ﹤0.01%
39,498
-13,215
-25% -$485K
ROKU icon
2605
PUT
Roku
ROKU
$22.7B
$1.42M ﹤0.01%
13,100
+7,100
+118% +$721K
NTSK
2606
Netskope Inc
NTSK
$6.01B
$1.41M ﹤0.01%
+80,522
New +$1.68M
ACRV icon
2607
Acrivon Therapeutics
ACRV
$74M
$1.41M ﹤0.01%
585,069
+265,864
+83% +$578K
CATY icon
2608
Cathay General Bancorp
CATY
$4.24B
$1.41M ﹤0.01%
29,078
-123,724
-81% -$5.95M
QQMG icon
2609
Invesco ESG NASDAQ 100 ETF
QQMG
$204M
$1.41M ﹤0.01%
33,200
+3,000
+10% +$127K
TMQ
2610
Trilogy Metals
TMQ
$656M
$1.4M ﹤0.01%
325,091
-1,630
-0.5% -$7.68K
ASYS icon
2611
Amtech Systems
ASYS
$272M
$1.4M ﹤0.01%
+111,437
New +$1M
PLYM
2612
DELISTED
Plymouth Industrial REIT
PLYM
$1.4M ﹤0.01%
63,874
-60,278
-49% -$1.32M
DE icon
2613
CALL
Deere & Co
DE
$168B
$1.4M ﹤0.01%
+3,000
New +$1.41M
TDAC
2614
Translational Development Acquisition Corp
TDAC
$238M
$1.39M ﹤0.01%
133,325
MLCO icon
2615
Melco Resorts & Entertainment
MLCO
$2.14B
$1.39M ﹤0.01%
183,790
+169,030
+1,145% +$1.42M
GTN icon
2616
Gray Television
GTN
$552M
$1.39M ﹤0.01%
286,914
-4,836
-2% -$23.7K
BROS icon
2617
Dutch Bros
BROS
$9.26B
$1.39M ﹤0.01%
22,632
-488,531
-96% -$27.8M
COHR icon
2618
PUT
Coherent
COHR
$74.2B
$1.38M ﹤0.01%
+7,500
New +$1.12M
GME icon
2619
PUT
GameStop
GME
$8.6B
$1.38M ﹤0.01%
68,900
-3,060,100
-98% -$68.7M
NOVT icon
2620
Novanta
NOVT
$6.29B
$1.38M ﹤0.01%
+11,618
New +$1.32M
ORGO icon
2621
Organogenesis Holdings
ORGO
$239M
$1.38M ﹤0.01%
266,660
+216,066
+427% +$1.05M
DAKT icon
2622
Daktronics
DAKT
$1.04B
$1.38M ﹤0.01%
69,700
-27,621
-28% -$528K
RGEN icon
2623
Repligen
RGEN
$9.25B
$1.38M ﹤0.01%
8,400
-86,461
-91% -$13.5M
AVNT icon
2624
Avient
AVNT
$4.19B
$1.37M ﹤0.01%
+43,891
New +$1.36M
BOC icon
2625
Boston Omaha
BOC
$436M
$1.37M ﹤0.01%
110,512
+14,287
+15% +$186K

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Two Sigma Investments's Q4 2025 Portfolio in Review

As of Q4 2025, Two Sigma Investments held 4,545 positions worth $70.9B, up 5.5% from $67.2B the previous quarter. Its ten largest holdings account for 4.9% of the portfolio.

Two Sigma Investments's Q4 2025 filing shows 899 new, 1,598 increased, 1,287 reduced and 504 closed positions. Its largest new stake was Vanguard Real Estate ETF: 3,573,400 shares worth $316M. The largest sale was State Street Financial Select Sector SPDR ETF, an estimated $547M.

By sector, the portfolio is most concentrated in Technology at 16% of assets, down from 16% a quarter earlier, followed by Financials and Industrials.

  • Two Sigma Investments's largest Q4 2025 buy was Vanguard Real Estate ETF: 3,573,400 shares worth $316M.
  • Two Sigma Investments added most to State Street Technology Select Sector SPDR ETF in Q4 2025, an estimated $395M increase.
  • Two Sigma Investments's biggest Q4 2025 reduction was State Street Financial Select Sector SPDR ETF, cutting an estimated $547M.
  • Two Sigma Investments fully exited State Street SPDR Dow Jones Industrial Average ETF Trust in Q4 2025, selling an estimated $240M.
  • Two Sigma Investments's ten largest holdings make up 4.9% of its $70.9B portfolio in Q4 2025.
  • Two Sigma Investments opened 899 new positions and closed 504 in Q4 2025.
  • Two Sigma Investments's portfolio value rose 5.5% quarter-over-quarter to $70.9B.

Based on Two Sigma Investments's 13F filing for Q4 2025, filed 17 Feb 2026.