Two Sigma Investments
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Two Sigma Investments’s Humacyte HUMA Stock Holding History

Two Sigma Investments’s Portfolio HUMA Stock Details HUMA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$108K Sell
177,536
-1,313,931
-88% -$1.37M ﹤0.01% 4379
2025
Q4 		$1.43M Buy
1,491,467
+124,883
+9% +$177K ﹤0.01% 2696
2025
Q3 		$2.38M Sell
1,366,584
-170,797
-11% -$335K ﹤0.01% 2016
2025
Q2 		$3.21M Buy
1,537,381
+950,940
+162% +$1.83M 0.01% 1521
2025
Q1 		$1,000K Sell
586,441
-332,656
-36% -$1.25M ﹤0.01% 2175
2024
Q4 		$4.64M Sell
919,097
-149,142
-14% -$738K 0.01% 1149
2024
Q3 		$5.81M Sell
1,068,239
-73,803
-6% -$487K 0.01% 1008
2024
Q2 		$5.48M Buy
1,142,042
+1,116,414
+4,356% +$5.81M 0.01% 968
2024
Q1 		$79.7K Sell
25,628
-307,048
-92% -$1.03M ﹤0.01% 2851
2023
Q4 		$945K Buy
332,676
+215,074
+183% +$552K ﹤0.01% 2115
2023
Q3 		$345K Buy
+117,602
New +$389K ﹤0.01% 2437
2023
Q1 		– Sell
-24,567
Closed -$51.8K – 3064
2022
Q4 		$51.8K Buy
+24,567
New +$74.6K ﹤0.01% 2587
2022
Q1 		– Sell
-31,061
Closed -$225K – 3404
2021
Q4 		$225K Buy
+31,061
New +$307K ﹤0.01% 3844

Other funds holding HUMA

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
AP
Antipodes Partners Royal Exchange, Australia $5.19B AUM 36.17% 1-Year Est. Return
GPP
Great Point Partners Greenwich, Connecticut $435M AUM 318.81% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return
AQR Capital Management
AQR Capital Management Greenwich, Connecticut $218B AUM 29.41% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Two Sigma Investments's HUMA Position: Q1 2026 in Review

Two Sigma Investments reduced its Humacyte (HUMA) stake by 88% in Q1 2026, selling an estimated $1.37M and leaving 177,536 shares worth $108K. The position accounts for ﹤0.01% of the portfolio, ranked #4379.

Two Sigma Investments first reported a position in HUMA in Q4 2021 and has held it in 13 quarters since. The position peaked at $5.81M in Q3 2024. 158 funds tracked by Wall St. Rank hold HUMA as of Q1 2026.

  • Two Sigma Investments held 177,536 shares of Humacyte worth $108K as of Q1 2026.
  • Two Sigma Investments sold 1,313,931 Humacyte shares in Q1 2026, an estimated $1.37M.
  • Humacyte made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #4379 holding.
  • Two Sigma Investments first reported a position in Humacyte in Q4 2021 and has held it in 13 quarters since.
  • Two Sigma Investments's Humacyte position peaked at $5.81M in Q3 2024.
  • 158 funds tracked by Wall St. Rank held Humacyte as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.