Two Sigma Investments
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Two Sigma Investments’s Sutro Biopharma STRO Stock Holding History

Two Sigma Investments’s Portfolio STRO Stock Details STRO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.62M Buy
65,176
+18,684
+40% +$338K ﹤0.01% 2917
2025
Q4 		$538K Buy
46,492
+6,813
+17% +$64.7K ﹤0.01% 3262
2025
Q3 		$345K Buy
39,679
+28,172
+245% +$240K ﹤0.01% 3158
2025
Q2 		$82.1K Buy
11,507
+1,919
+20% +$15.7K ﹤0.01% 3017
2025
Q1 		$62.4K Sell
9,588
-22,041
-70% -$347K ﹤0.01% 3025
2024
Q4 		$582K Sell
31,629
-17,548
-36% -$536K ﹤0.01% 2467
2024
Q3 		$1.7M Sell
49,177
-1,183
-2% -$46.4K ﹤0.01% 1773
2024
Q2 		$1.48M Buy
50,360
+1,784
+4% +$70.5K ﹤0.01% 1767
2024
Q1 		$2.74M Buy
48,576
+16,257
+50% +$718K 0.01% 1277
2023
Q4 		$1.39M Buy
+32,319
New +$1.03M ﹤0.01% 1874
2023
Q3 		– Sell
-13,582
Closed -$632K – 3207
2023
Q2 		$632K Sell
13,582
-20,459
-60% -$1.02M ﹤0.01% 2216
2023
Q1 		$1.57M Buy
34,041
+10,251
+43% +$651K ﹤0.01% 1562
2022
Q4 		$1.92M Buy
23,790
+6,081
+34% +$423K 0.01% 1335
2022
Q3 		$983K Sell
17,709
-581
-3% -$34.4K ﹤0.01% 1480
2022
Q2 		$953K Buy
18,290
+1,999
+12% +$112K ﹤0.01% 1570
2022
Q1 		$1.34M Buy
16,291
+4,983
+44% +$474K ﹤0.01% 1555
2021
Q4 		$1.68M Sell
11,308
-11,440
-50% -$2.05M ﹤0.01% 2085
2021
Q3 		$4.3M Buy
22,748
+2,344
+11% +$446K 0.01% 1352
2021
Q2 		$3.79M Buy
20,404
+8,553
+72% +$1.67M 0.01% 1374
2021
Q1 		$2.7M Buy
11,851
+6,966
+143% +$1.65M 0.01% 1475
2020
Q4 		$1.06M Sell
4,885
-5,888
-55% -$975K ﹤0.01% 1960
2020
Q3 		$1.08M Buy
+10,773
New +$1.02M ﹤0.01% 1698

Other funds holding STRO

BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
AAA
Affinity Asset Advisors New York $1.94B AUM 374.45% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.03B AUM 214.94% 1-Year Est. Return
KCM
Kynam Capital Management Princeton, New Jersey $1.62B AUM 138.67% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
EAM
Eventide Asset Management Boston, Massachusetts $6.05B AUM 76.64% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return

Two Sigma Investments's STRO Position: Q1 2026 in Review

Two Sigma Investments increased its Sutro Biopharma (STRO) stake by 40% in Q1 2026, buying an estimated $338K and bringing the position to 65,176 shares worth $1.62M. The position accounts for ﹤0.01% of the portfolio, ranked #2917.

Two Sigma Investments first reported a position in STRO in Q3 2020 and has held it in 22 quarters since. The position peaked at $4.3M in Q3 2021. 78 funds tracked by Wall St. Rank hold STRO as of Q1 2026.

  • Two Sigma Investments held 65,176 shares of Sutro Biopharma worth $1.62M as of Q1 2026.
  • Two Sigma Investments bought 18,684 Sutro Biopharma shares in Q1 2026, an estimated $338K.
  • Sutro Biopharma made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #2917 holding.
  • Two Sigma Investments first reported a position in Sutro Biopharma in Q3 2020 and has held it in 22 quarters since.
  • Two Sigma Investments's Sutro Biopharma position peaked at $4.3M in Q3 2021.
  • 78 funds tracked by Wall St. Rank held Sutro Biopharma as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.