Two Sigma Investments
SOPH icon

Two Sigma Investments’s SOPHiA GENETICS SOPH Stock Holding History

Two Sigma Investments’s Portfolio SOPH Stock Details SOPH Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$337K Buy
58,333
+48,135
+472% +$244K ﹤0.01% 4453
2026
Q1 		$50.5K Buy
+10,198
New +$49.6K ﹤0.01% 4452
2022
Q3 		– Sell
-13,646
Closed -$49K – 2798
2022
Q2 		$49K Buy
+13,646
New +$69.2K ﹤0.01% 2348

Other funds holding SOPH

GIM
Generation Investment Management London, United Kingdom $10.3B AUM 4.84% 1-Year Est. Return
ACM
AIGH Capital Management Baltimore, Maryland $1.59B AUM 855.46% 1-Year Est. Return
ACM
AKRE Capital Management Middleburg, Virginia $5.12B AUM 19.08% 1-Year Est. Return
RA
Royce & Associates New York $12.4B AUM 64.17% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $204B AUM 27.99% 1-Year Est. Return
Ameriprise
Ameriprise Minneapolis, Minnesota $495B AUM 43.24% 1-Year Est. Return
BPC
Banque Pictet & Cie Geneva 73, Switzerland $16B AUM 29.1% 1-Year Est. Return
AIC
AWM Investment Company New York $1.15B AUM 201.65% 1-Year Est. Return
SCM
Soleus Capital Management Greenwich, Connecticut $2.9B AUM 169.69% 1-Year Est. Return
SAM
Silvercrest Asset Management New York $15.3B AUM 40.56% 1-Year Est. Return

Two Sigma Investments's SOPH Position: Q2 2026 in Review

Two Sigma Investments increased its SOPHiA GENETICS (SOPH) stake by 472% in Q2 2026, buying an estimated $244K and bringing the position to 58,333 shares worth $337K. The position accounts for ﹤0.01% of the portfolio, ranked #4453.

Two Sigma Investments first reported a position in SOPH in Q2 2022 and has held it in 3 quarters since. 71 funds tracked by Wall St. Rank hold SOPH as of Q2 2026.

  • Two Sigma Investments held 58,333 shares of SOPHiA GENETICS worth $337K as of Q2 2026.
  • Two Sigma Investments bought 48,135 SOPHiA GENETICS shares in Q2 2026, an estimated $244K.
  • SOPHiA GENETICS made up ﹤0.01% of Two Sigma Investments's portfolio in Q2 2026, its #4453 holding.
  • Two Sigma Investments first reported a position in SOPHiA GENETICS in Q2 2022 and has held it in 3 quarters since.
  • 71 funds tracked by Wall St. Rank held SOPHiA GENETICS as of Q2 2026.

Based on Two Sigma Investments's 13F filing for Q2 2026, filed 14 Aug 2026.