Two Sigma Investments
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Two Sigma Investments’s Relmada Therapeutics RLMD Stock Holding History

Two Sigma Investments’s Portfolio RLMD Stock Details RLMD Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.84M Sell
408,095
-164,740
-29% -$779K ﹤0.01% 2478
2025
Q4 		$2.77M Buy
572,835
+399,221
+230% +$1.34M ﹤0.01% 2189
2025
Q3 		$349K Buy
173,614
+78,197
+82% +$75K ﹤0.01% 3148
2025
Q2 		$57.3K Sell
95,417
-75,127
-44% -$38.6K ﹤0.01% 3056
2025
Q1 		$46K Buy
170,544
+42,965
+34% +$14.2K ﹤0.01% 3052
2024
Q4 		$66.3K Sell
127,579
-63,736
-33% -$155K ﹤0.01% 3017
2024
Q3 		$620K Sell
191,315
-11,946
-6% -$38.7K ﹤0.01% 2362
2024
Q2 		$610K Sell
203,261
-23,778
-10% -$86K ﹤0.01% 2271
2024
Q1 		$1.06M Sell
227,039
-75,705
-25% -$365K ﹤0.01% 1928
2023
Q4 		$1.25M Buy
302,744
+105,547
+54% +$313K ﹤0.01% 1942
2023
Q3 		$592K Sell
197,197
-107,689
-35% -$320K ﹤0.01% 2208
2023
Q2 		$750K Sell
304,886
-99,389
-25% -$275K ﹤0.01% 2115
2023
Q1 		$914K Sell
404,275
-122,887
-23% -$424K ﹤0.01% 1922
2022
Q4 		$1.84M Buy
527,162
+475,274
+916% +$4.17M 0.01% 1358
2022
Q3 		$1.92M Buy
51,888
+40,537
+357% +$1.12M 0.01% 1167
2022
Q2 		$216K Buy
11,351
+851
+8% +$18.6K ﹤0.01% 2134
2022
Q1 		$283K Buy
+10,500
New +$217K ﹤0.01% 2232

Other funds holding RLMD

Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
SCM
Squadron Capital Management Westmont, Illinois $273M AUM
SSC
Spruce Street Capital New York $416M AUM
VA
VR Adviser New York $2.68B AUM 422.73% 1-Year Est. Return
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return

Two Sigma Investments's RLMD Position: Q1 2026 in Review

Two Sigma Investments reduced its Relmada Therapeutics (RLMD) stake by 29% in Q1 2026, selling an estimated $779K and leaving 408,095 shares worth $2.84M. The position accounts for ﹤0.01% of the portfolio, ranked #2478.

Two Sigma Investments first reported a position in RLMD in Q1 2022 and has held it in 17 quarters since. 103 funds tracked by Wall St. Rank hold RLMD as of Q1 2026.

  • Two Sigma Investments held 408,095 shares of Relmada Therapeutics worth $2.84M as of Q1 2026.
  • Two Sigma Investments sold 164,740 Relmada Therapeutics shares in Q1 2026, an estimated $779K.
  • Relmada Therapeutics made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #2478 holding.
  • Two Sigma Investments first reported a position in Relmada Therapeutics in Q1 2022 and has held it in 17 quarters since.
  • 103 funds tracked by Wall St. Rank held Relmada Therapeutics as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.