Two Sigma Investments
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Two Sigma Investments’s Regeneron Pharmaceuticals REGN Stock Holding History

Two Sigma Investments’s Portfolio REGN Stock Details REGN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2022
Q1 		– Sell
-18,300
Closed -$11.6M – 4031
2021
Q4 		$11.6M Sell
18,300
-3,600
-16% -$2.21M 0.02% 710
2021
Q3 		$13.3M Sell
21,900
-5,400
-20% -$3.35M 0.03% 638
2021
Q2 		$15.2M Buy
27,300
+7,900
+41% +$4M 0.03% 604
2021
Q1 		$9.18M Sell
19,400
-3,300
-15% -$1.61M 0.02% 735
2020
Q4 		$11M Buy
22,700
+14,300
+170% +$7.72M 0.03% 560
2020
Q3 		$4.7M Buy
+8,400
New +$5.09M 0.02% 819
2020
Q2 		– Sell
-10,500
Closed -$5.13M – 3430
2020
Q1 		$5.13M Sell
10,500
-8,100
-44% -$3.34M 0.04% 489
2019
Q4 		$6.98M Buy
18,600
+2,300
+14% +$774K 0.02% 776
2019
Q3 		$4.52M Buy
16,300
+1,600
+11% +$473K 0.02% 918
2019
Q2 		$4.6M Buy
14,700
+2,700
+23% +$899K 0.02% 942
2019
Q1 		$4.93M Buy
12,000
+9,000
+300% +$3.71M 0.02% 969
2018
Q4 		$1.12M Buy
3,000
+2,000
+200% +$732K ﹤0.01% 1584
2018
Q3 		$404K Sell
1,000
-22,700
-96% -$8.64M ﹤0.01% 2595
2018
Q2 		$8.18M Sell
23,700
-1,300
-5% -$407K 0.02% 751
2018
Q1 		$8.61M Buy
25,000
+22,300
+826% +$7.76M 0.03% 662
2017
Q4 		$1.01M Sell
2,700
-5,800
-68% -$2.35M ﹤0.01% 1970
2017
Q3 		$3.8M Buy
+8,500
New +$4.04M 0.01% 938
2017
Q2 		– Sell
-4,000
Closed -$1.55M – 3225
2017
Q1 		$1.55M Buy
4,000
+2,000
+100% +$741K 0.01% 1610
2016
Q4 		$734K Sell
2,000
-13,000
-87% -$4.94M ﹤0.01% 2233
2016
Q3 		$6.03M Buy
15,000
+12,000
+400% +$4.81M 0.02% 782
2016
Q2 		$1.05M Buy
+3,000
New +$1.16M ﹤0.01% 1696
2016
Q1 		– Sell
-5,000
Closed -$2.71M – 3074
2015
Q4 		$2.71M Buy
5,000
+2,000
+67% +$1.08M 0.01% 930
2015
Q3 		$1.4M Buy
+3,000
New +$1.61M 0.01% 1012
2015
Q2 		– Sell
-1,000
Closed -$451K – 3046
2015
Q1 		$451K Buy
+1,000
New +$424K ﹤0.01% 2031

Other funds holding REGN

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Dodge & Cox
Dodge & Cox San Francisco, California $182B AUM 14.68% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
Franklin Resources
Franklin Resources San Mateo, California $408B AUM 30.18% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
N
Nuveen Charlotte, North Carolina $369B AUM 31.66% 1-Year Est. Return

Two Sigma Investments's REGN Position: Q1 2026 in Review

Two Sigma Investments increased its Regeneron Pharmaceuticals (REGN) stake by 189% in Q1 2026, buying an estimated $407M and bringing the position to 812,236 shares worth $628M. The position accounts for 0.51% of the portfolio, ranked #24.

Two Sigma Investments first reported a position in REGN in Q2 2013 and has held it in 36 quarters since. 1,392 funds tracked by Wall St. Rank hold REGN as of Q1 2026.

  • Two Sigma Investments held 812,236 shares of Regeneron Pharmaceuticals worth $628M as of Q1 2026.
  • Two Sigma Investments bought 531,085 Regeneron Pharmaceuticals shares in Q1 2026, an estimated $407M.
  • Regeneron Pharmaceuticals made up 0.51% of Two Sigma Investments's portfolio in Q1 2026, its #24 holding.
  • Two Sigma Investments first reported a position in Regeneron Pharmaceuticals in Q2 2013 and has held it in 36 quarters since.
  • 1,392 funds tracked by Wall St. Rank held Regeneron Pharmaceuticals as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.